Comparison of the effect of resistance versus aerobic exercise on the serum levels of salusin-α and salusin-β, lipid profile and insulin resistance in overweight/obese women

Objectives. - Increased body fat level or obesity is related to dyslipidemia, high blood pressure, insulin resistance, respiratory disorders and type 2 diabetes and increases intracellular inflammatory processes and arterial injuries. Equipment and methods. - The study participants were 39 overweight/obese women living in Ilam City, Iran who were randomly assigned into three group of aerobic exercise group (treadmill at 50-70% heart rate reserve [HRR]) (n = 13), resistance exercise group (8 to 16 repetitions of 7 upper and lower body exercises at 60% to 80% of 1 repetition maximum) and control group. Training was conducted through three sessions per week for 8 weeks. Repeated measures ANOVA with Bonferroni post-hoc tests were employed to analyze the data (P <= 0.05). Results. - The findings showed that the levels of salusin-alpha (P = 0.192), salusin-beta (P = 0.069), high-density lipoprotein (HDL) (P = 0.862), low-density lipoprotein (LDL) (P = 0.941), triglycerides (TG) (P = 0.287), and body fat percentage and insulin resistance (P = 0.99) did not show any significant difference between aerobic and resistance exercise groups. However, a significant difference was observed between the aerobic and resistance exercise groups in total cholesterol (P = 0.007). In general, the results of the present study show that resistance and aerobic exercises have beneficial effects in the prevention of atherosclerosis cardiovascular diseases in obese and overweight women. (c) 2023 Elsevier Masson SAS. All rights reserved.