SARS-CoV-2 und Allergie-was haben wir gelernt?

被引：2

作者：

Alexiou, A. ^{[1
]}

Irmer, M. L. ^{[1
]}

Bauer, A. ^{[2
]}

Treudler, R. ^{[3
]}

Wurpts, G. ^{[4
]}

Dickel, H. ^{[5
]}

Buhl, T. ^{[6
]}

Jung, A. ^{[7
]}

Muelleneisen, N. ^{[8
]}

Schuh, S. ^{[9
]}

Timmermann, H. ^{[10
]}

Heine, G. ^{[11
]}

Wedi, B. ^{[12
]}

Brockow, K. ^{[13
]}

Worm, M. ^{[1
]}

机构：

[1] Univ Med Berlin, Klin Dermatol Venerol & Allergol, Allergol & Immunol, Campus Charite Mitte, Berlin, Germany

[2] Tech Univ Dresden, Univ Klinikum Carl Gustav Carus, Comprehens Allergy Ctr CAC, Klin & Poliklin Dermatol, Dresden, Germany

[3] Univ Med Leipzig, Klin Dermatol Venerol & Allergol, Leipziger Interdisziplinares Ctr Allergol CAC, Leipzig, Germany

[4] Univ Klin RWTH Aachen, Aachener Comprehens Allergy Ctr ACAC, Klin Dermatol & Allergol, Aachen, Germany

[5] Ruhr Univ Bochum, Univ Klinikum, St Josef Hosp, Abt Allergol Berufs & Umweltdermatol,Klin Dermato, Bochum, Germany

[6] Georg August Univ, Univ Med Gottingen, Klin Dermatol Venerol & Allergol, Gottingen, Germany

[7] Univ Klinikum Giessen, Klin Dermatol Venerol & Allergol, Giessen, Germany

[8] Asthma & Allergiezentrum Leverkusen, Leverkusen, Germany

[9] Univ klinikum Augsburg, Klin Dermatol & Allergol, Standort Med Campus Sud, Augsburg, Germany

[10] Schwerpunktpraxis Colonnaden, Hamburg, Germany

[11] Univ Klinikum Schleswig Holstein, Klin Dermatol Venerol & Allergol, Campus Kiel, Kiel, Germany

[12] Hannover Med Sch, Comprehens Allergy Ctr CAC, Klin Dermatol Allergol & Venerol, Hannover, Germany

[13] Tech Univ Munich, Klin & Poliklin Dermatol & Allergol Biederstein, Munich, Germany

来源：

ALLERGOLOGIE | 2023年 / 46卷 / 06期

关键词：

SARS-CoV-2; anaphylaxis; hypersensitivity; vaccination; VACCINATION;

D O I：

10.5414/ALX02411

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The aim of vaccination is to trigger an antigen-specific immune response in order to protect the organism from an infectious disease. Rarely, vaccination can trigger excessive immune reactions. Here, we report on the results of consultations and allergy testing carried out by allergy centers in Germany in 2021. Approximately 8,000 requested consultations were reported by a total of 13 centers, with direct contact by phone and/or in person (n = 2,467). The results show that only in exceptional cases the recommendation for vaccination could not be given or could be given only in conjunction with intensified safety measures. Based on 3 exemplary cases, we show the allergy testing procedure in 3 selected patients who were successfully vaccinated with good tolerability of the vaccine. An important differential diagnosis of immediate reactions in the context of vaccination are vasovagal reactions. A possible distinction criterion is the absence of skin symptoms, such as urticaria or swelling of the mucous membranes. The Germany-wide allergist capacity was pushed to its limits during the COVID-19 pandemic. Thus, the indication for further allergy diagnostics should be critically considered in order to avoid unnecessary skin tests. The early implementation of a standardized procedure made it possible to show that the risk of allergy to a COVID-19 vaccine is very low.

引用

页码：382 / 391

页数：10

共 19 条

[1] PEG allergy - A COVID-19 pandemic-made problem? A German perspective [J].