Mechanism of fibroblast growth factor 21 in cardiac remodeling

被引：4
|
作者：
Zhao, Zeyu [1 ]
Cui, Xuemei [2 ]
Liao, Zhangping [3 ]
机构：
[1] Nanchang Univ, Queen Mary Coll, Nanchang, Peoples R China
[2] Nanchang Univ, Clin Med Coll 4, Nanchang, Peoples R China
[3] Nanchang Univ, Sch Pharmaceut Sci, Jiangxi Prov Key Lab Basic Pharmacol, Nanchang, Peoples R China
来源：
FRONTIERS IN CARDIOVASCULAR MEDICINE | 2023年 / 10卷
基金：
中国国家自然科学基金;
关键词：
fibroblast growth factor 21 (FGF21); heart remodeling; energy metabolism; oxidation; inflammation; autophagy; OXIDATIVE STRESS; DIABETIC CARDIOMYOPATHY; VENTRICULAR DYSFUNCTION; MYOCARDIAL-INFARCTION; HEART-FAILURE; MITOCHONDRIAL DYSFUNCTION; NADPH OXIDASE; CELL-DEATH; FGF21; INFLAMMATION;
D O I：
10.3389/fcvm.2023.1202730
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Cardiac remodeling is a basic pathological process that enables the progression of multiple cardiac diseases to heart failure. Fibroblast growth factor 21 is considered a regulator in maintaining energy homeostasis and shows a positive role in preventing damage caused by cardiac diseases. This review mainly summarizes the effects and related mechanisms of fibroblast growth factor 21 on pathological processes associated with cardiac remodeling, based on a variety of cells of myocardial tissue. The possibility of Fibroblast growth factor 21 as a promising treatment for the cardiac remodeling process will also be discussed.
引用
收藏
页数：9
相关论文
共 50 条
  • [41] Potential roles of fibroblast growth factor 21 in the brain
    Piangkwan Sa-nguanmoo
    Nipon Chattipakorn
    Siriporn C. Chattipakorn
    Metabolic Brain Disease, 2016, 31 : 239 - 248
  • [42] The Role of Fibroblast Growth Factor 21 (FGF21) in the Pancreas
    Singhal, Garima
    Fisher, Ffolliott Martin
    El Ouaamari, Abdelfattah
    Kulkarni, Rohit N.
    Flier, Jeffery S.
    Flier, Eleftheria Maratos
    DIABETES, 2014, 63 : A559 - A559
  • [43] Fibroblast growth factor 21: from pharmacology to physiology
    Kliewer, Steven A.
    Mangelsdorf, David J.
    AMERICAN JOURNAL OF CLINICAL NUTRITION, 2010, 91 (01): : 254S - 257S
  • [44] Potential roles of fibroblast growth factor 21 in the brain
    Sa-nguanmoo, Piangkwan
    Chattipakorn, Nipon
    Chattipakorn, Siriporn C.
    METABOLIC BRAIN DISEASE, 2016, 31 (02) : 239 - 248
  • [45] Fibroblast growth factor 21 in chronic kidney disease
    Anuwatmatee, Sahapab
    Tang, Shudi
    Wu, Ben J.
    Rye, Kerry-Anne
    Ong, Kwok Leung
    CLINICA CHIMICA ACTA, 2019, 489 : 196 - 202
  • [46] Fibroblast Growth Factor 21 Signaling: The Liver in Focus
    Mahlapuu, Margit
    Marschall, Hanns-Ulrich
    HEPATOLOGY, 2016, 64 (02) : 333 - 335
  • [47] Fibroblast growth factor 21: A "rheostat" for metabolic regulation?
    She, Qin-Ying
    Bao, Jing-Fu
    Wang, Hui-Zhen
    Liang, Huixin
    Huang, Wentao
    Wu, Jing
    Zhong, Yiwen
    Ling, Hanxin
    Li, Aiqing
    Qin, Shu-Lan
    METABOLISM-CLINICAL AND EXPERIMENTAL, 2022, 130
  • [48] Fibroblast Growth Factor 21 Corrects Obesity in Mice
    Coskun, Tamer
    Bina, Holly A.
    Schneider, Michael A.
    Dunbar, James D.
    Hu, Charlie C.
    Chen, Yanyun
    Moller, David E.
    Kharitonenkov, Alexei
    ENDOCRINOLOGY, 2008, 149 (12) : 6018 - 6027
  • [49] Fibroblast growth factor 21 in chronic kidney disease
    de Albuquerque Suassuna, Paulo Giovanni
    de Paula, Rogerio Baumgratz
    Sanders-Pinheiro, Helady
    Moe, Orson W.
    Hu, Ming-Chang
    JOURNAL OF NEPHROLOGY, 2019, 32 (03) : 365 - 377
  • [50] Fibroblast growth factor 21 in chronic kidney disease
    Paulo Giovanni de Albuquerque Suassuna
    Rogério Baumgratz de Paula
    Hélady Sanders-Pinheiro
    Orson W. Moe
    Ming-Chang Hu
    Journal of Nephrology, 2019, 32 : 365 - 377
12345