Acute Myeloid Leukemia with NPM1 Mutation and Disseminated Leukemia Cutis: Achievement of Molecular Complete Remission by Venetoclax/Azacitidine Combination in a Very Old Patient

被引:6
|
作者
Niscola, Pasquale [1 ,5 ]
Mazzone, Carla [1 ]
Fratoni, Stefano [2 ]
Ardu, Nicolina Rita [1 ]
Cesini, Laura [1 ]
Giovannini, Marco [1 ]
Ottone, Tiziana [4 ]
Anemona, Lucia [3 ]
Voso, Maria Teresa [4 ]
de Fabritiis, Paolo [1 ]
机构
[1] ASL Roma 2, S Eugenio Hosp, Hematol Unit, Rome, Italy
[2] ASL Roma 2, S Eugenio Hosp, Pathol Dept, Rome, Italy
[3] Univ Roma Tor Vergata, Dept Biomed & Prevent, Anat Pathol, Rome, Italy
[4] Univ Roma Tor Vergata, Dept Biomed & Prevent, Rome, Italy
[5] S Eugenio Hosp, Hematol Unit, Piazzale Umanesimo 10, I-00144 Rome, Italy
关键词
Acute myeloid leukemia; Leukemia cutis; Nucleophosmin-1; Venetoclax; azacitidine; VENETOCLAX;
D O I
10.1159/000531101
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We describe a case of acute myeloid leukemia with NPM1 mutation and disseminated leukemia cutis in a very old patient, who achieved a long-lasting response to the azacitidine/venetoclax combination with molecular complete remission, given the potential value of this rarely observed clinical outcome.
引用
收藏
页码:408 / 412
页数:5
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