The role of heterochromatin in 3D genome organization during preimplantation development

被引：1
作者：
Rang, Franka J. [1 ,2 ,3 ]
Kind, Jop [1 ,2 ,3 ,4 ]
Guerreiro, Isabel [1 ,2 ,3 ]
机构：
[1] Royal Netherlands Acad Arts & Sci KNAW, Hubrecht Inst, Uppsalalaan 8, NL-3584 CT Utrecht, Netherlands
[2] Univ Med Ctr Utrecht, Uppsalalaan 8, NL-3584 CT Utrecht, Netherlands
[3] Oncode Inst, Utrecht, Netherlands
[4] Radboud Univ Nijmegen, Radboud Inst Mol Life Sci, Fac Sci, Dept Mol Biol, Houtlaan 4, NL-6525 XZ Nijmegen, Netherlands
来源：
CELL REPORTS | 2023年 / 42卷 / 04期
关键词：
NUCLEAR LAMINA INTERACTIONS; POLYCOMB-GROUP PROTEINS; PHASE-SEPARATION; CONSTITUTIVE HETEROCHROMATIN; CHROMATIN ARCHITECTURE; HISTONE MODIFICATIONS; MOUSE EMBRYOS; LOOP; REVEALS; DOMAIN;
D O I：
10.1016/j.celrep.2023.112248
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
During the early stages of mammalian development, the epigenetic state of the parental genome is completely reprogrammed to give rise to the totipotent embryo. An important aspect of this remodeling con-cerns the heterochromatin and the spatial organization of the genome. While heterochromatin and genome organization are intricately linked in pluripotent and somatic systems, little is known about their relationship in the totipotent embryo. In this review, we summarize the current knowledge on the reprogramming of both regulatory layers. In addition, we discuss available evidence on their relationship and put this in the context of findings in other systems.
引用
收藏
页码：1 / 12
页数：12
相关论文
共 50 条
  • [31] 3D genome organization in the central nervous system, implications for neuropsychological disorders
    Sun, Daijing
    Weng, Jie
    Dong, Yuhao
    Jiang, Yan
    JOURNAL OF GENETICS AND GENOMICS, 2021, 48 (12) : 1045 - 1056
  • [32] The Dynamic 3D Genome in Gametogenesis and Early Embryonic Development
    Li, Feifei
    An, Ziyang
    Zhang, Zhihua
    CELLS, 2019, 8 (08)
  • [33] 3D genome alterations and editing in pathology
    Tiukacheva, Eugenia A.
    V. Ulianov, Sergey V.
    Karpukhina, Anna
    V. Razin, Sergey V.
    Vassetzky, Yegor
    MOLECULAR THERAPY, 2023, 31 (04) : 924 - 933
  • [34] Enhancer Dysfunction in 3D Genome and Disease
    Xia, Ji-Han
    Wei, Gong-Hong
    CELLS, 2019, 8 (10)
  • [35] Comparative 3D genome architecture in vertebrates
    Li, Diyan
    He, Mengnan
    Tang, Qianzi
    Tian, Shilin
    Zhang, Jiaman
    Li, Yan
    Wang, Danyang
    Jin, Long
    Ning, Chunyou
    Zhu, Wei
    Hu, Silu
    Long, Keren
    Ma, Jideng
    Liu, Jing
    Zhang, Zhihua
    Li, Mingzhou
    BMC BIOLOGY, 2022, 20 (01)
  • [36] Advancements in mapping 3D genome architecture
    McKay, Daniel J.
    Stutzman, Alexis, V
    Dowen, Jill M.
    METHODS, 2020, 170 : 75 - 81
  • [37] Organizational principles of 3D genome architecture
    Rowley, M. Jordan
    Corces, Victor G.
    NATURE REVIEWS GENETICS, 2018, 19 (12) : 789 - 800
  • [38] Identification of Nucleolus-Associated Chromatin Domains Reveals a Role for the Nucleolus in 3D Organization of the A. thaliana Genome
    Pontvianne, Frederic
    Carpentier, Marie-Christine
    Durut, Nathalie
    Pavlistova, Veronika
    Jaske, Karin
    Schorova, Sarka
    Parrinello, Hugues
    Rohmer, Marine
    Pikaard, Craig S.
    Fojtova, Miloslava
    Fajkus, Jiri
    Saez-Vasquez, Julio
    CELL REPORTS, 2016, 16 (06): : 1574 - 1587
  • [39] The Hierarchy of the 3D Genome
    Gibcus, Johan H.
    Dekker, Job
    MOLECULAR CELL, 2013, 49 (05) : 773 - 782
  • [40] Comparing 3D Genome Organization in Multiple Species Using Phylo-HMRF
    Yang, Yang
    Zhang, Yang
    Ren, Bing
    Dixon, Jesse R.
    Ma, Jian
    CELL SYSTEMS, 2019, 8 (06) : 494 - +
12345