Visible light-catalyzed intermolecular [2+2] cycloaddition of 1,2-dihydropyridines: A combined experimental and DFT study

被引：1

作者：

He, Yimeng ^{[1
]}

Wang, Huiqin ^{[1
]}

Yang, Yifan ^{[1
]}

Yan, Hong ^{[1
]}

机构：

[1] Beijing Univ Technol, Fac Environm & Life, Beijing 100124, Peoples R China

来源：

TETRAHEDRON | 2023年 / 136卷

基金：

北京市自然科学基金;

关键词：

1; 2-Dihydropyridines; 2+2] Cycloaddition reaction; Synthesis; Theoretical calculations; 1,4-DIHYDROPYRIDINES; PHOTOCYCLOADDITION; DERIVATIVES; DISCOVERY; OLEFINS; DESIGN; PATH; TOOL;

D O I：

10.1016/j.tet.2023.133357

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In this article, the intermolecular [2+2] cycloaddition of 1,2-dihydropyridines was achieved for the first time by visible light-catalyzed. A series of novel and complex cyclobutane derivatives, the dimers of diethyl 1,2-diaryl-1,2-dihydropyridine-3,5-dicarboxylate, were synthesized efficiently with visible light catalysts under the irradiation of blue LED lamps. The density functional theory and time-dependent density functional theory were used to elucidate the detailed reaction processes, such as the reaction mechanism and the stereoselectivity of cycloaddition products. (c) 2023 Published by Elsevier Ltd.

引用

页数：10

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