First-in-Human Study of the CD123 NK Cell Engager SAR443579 in Relapsed or Refractory Acute Myeloid Leukemia, B-Cell Acute Lymphoblastic Leukemia or High RiskMyelodysplasia: Updated Safety, Efficacy, Pharmacokinetics and Pharmacodynamics

被引：12

作者：

Bajel, Ashish ^{[1
,2
]}

Garciaz, Sylvain ^{[3
]}

Desai, Pinkal ^{[4
]}

Huls, Gerwin A. ^{[5
]}

Maiti, Abhishek ^{[6
]}

Jongen-Lavrencic, Mojca ^{[7
]}

Boissel, Nicolas ^{[8
]}

De Botton, Stephane ^{[9
]}

de Leeuw, David C. ^{[10
]}

Fleming, Shaun ^{[11
]}

Zwaan, C. Michel ^{[12
]}

Arellano, Martha ^{[13
]}

Avigan, David ^{[14
]}

Saultz, Jennifer N. ^{[15
]}

Mantzaris, Ioannis ^{[16
]}

Jensen, Kyle ^{[17
]}

Wagenaar, Timothy ^{[17
]}

Mi, Gu ^{[17
]}

Ziti-Ljajic, Samira ^{[18
]}

Draganov, Dobrin ^{[17
]}

Abbadessa, Giovanni ^{[17
]}

Stein, Anthony Selwyn ^{[19
]}

机构：

[1] Peter MacCallum Canc Ctr, Melbourne, Vic, Australia

[2] Royal Melbourne Hosp, Melbourne, Vic, Australia

[3] Inst Paoli Calmettes, Marseille, France

[4] Weill Cornell Med, New York, NY USA

[5] Univ Med Ctr Groningen, Groningen, Netherlands

[6] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX 77030 USA

[7] Erasmus MC, Rotterdam, Netherlands

[8] Hop St Louis, Paris, France

[9] Inst Gustave Roussy, Paris, France

[10] Univ Amsterdam, Med Ctr, Amsterdam, Netherlands

[11] Alfred Hlth, Melbourne, Vic, Australia

[12] Prinses Maxima Ctr Pediat Oncol Res, Utrecht, Netherlands

[13] Emory Univ, Sch Med, Atlanta, GA USA

[14] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Boston, MA 02115 USA

[15] Oregon Hlth & Sci Univ, Portland, OR 97201 USA

[16] Montefiore Med Ctr, Dept Oncol, 111 E 210Th St, Bronx, NY 10467 USA

[17] Sanofi, Cambridge, MA USA

[18] Sanofi, Chilly Mazarin, France

[19] City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USA

来源：

BLOOD | 2023年 / 142卷

关键词：

D O I：

10.1182/blood-2023-173162

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：5