Case report: 'Photodynamics of Subependymal Giant Cell Astrocytoma with 5-Aminolevulinic acid'

被引：0

作者：

Ghani, Imran ^{[1
,4
]}

Patel, Sabina ^{[1
,4
]}

Ghimire, Prajwal ^{[2
,4
]}

Bodi, Istvan ^{[3
]}

Bhangoo, Ranjeev ^{[4
]}

Vergani, Francesco ^{[4
]}

Ashkan, Keyoumars ^{[4
]}

Lavrador, Jose Pedro ^{[1
,4
]}

机构：

[1] Kings Neuro Lab, Dept Neurosurg, London, England

[2] Kings Coll London, Sch Biomed Engn & Imaging Studies, London, England

[3] Kings Coll Hosp NHS Fdn Trust, Dept Neuropathol, London, England

[4] Kings Coll Hosp NHS Fdn Trust, Dept Neurosurg, London, England

来源：

FRONTIERS IN SURGERY | 2023年 / 9卷

关键词：

5-aminolevulinic acid; fluorescence; tuberous sclerosis; subependymal giant cell astrocytoma; low grade glioma; minimal invasive parafascicular approach; TUBEROUS SCLEROSIS; GLIOMAS; TUMORS;

D O I：

10.3389/fsurg.2022.1065979

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Subependymal Giant Cell Astrocytoma (SEGA) is a common diagnosis in patients with Tuberous Sclerosis. Although surgical treatment is often required, resection may entail a significant risk for cognitive function given the anatomical relation with critical structures such as the fornices and subgenual area. Therefore, target subtotal resections using minimal invasive approaches focused in the higher metabolic areas are valuable options to preserve quality of life while addressing specific problems caused by the tumor, such as hydrocephalus or progressive growth of a specific component of the tumor. In this report, the authors explore the potential role of 5-ALA in the identification of highly metabolic areas during SEGA resection in the context of minimal invasive approaches.

引用

页数：7