In Vitro Antibacterial Activity of Ethanolic Thyme Extract against Porphyromonas gingivalis Isolated from Periodontal Pocket

. Thyme extracts have the ability to inhibit both gram negative and positive facultative bac- terial growth and inhibits plaque on the surfaces of the teeth. Therefore, the aim of this study to evalu- ate the antibacterial properties of thyme ethanolic extract towards P. gingivalis isolated clinically from periodontal pocket. The antibacterial susceptibility, minimum inhibition concentration (MIC), and min- imum bactericidal concentration (MBC) of ethanolic thyme extract against P. gingivalis were conducted by utilizing agar diffusion and 2-fold serial macro dilution methods. Phytochemical analysis was carried out using gas chromatography-mass spectrometry (GC-MS). P. gingivalis verification was done by us- ing PCR test. P. gingivalis was sensitive to all concentrations of thyme extract. MIC was 0.78 mg/mL, and MBC was 1.56 mg/mL against P. gingivalis. This could point to a potentially effective substitute al- ternative to conventional drugs which used as an adjuvant in the treatment of periodontitis.