A near-infrared fluorescent nanoprobe for senescence-associated β-galactosidase sensing in living cells

被引:4
|
作者
Zhao, Ye [1 ]
Sun, Shan [2 ]
Lyu, Yan [1 ]
Gao, Mengyao [1 ]
Lin, Hengwei [1 ,2 ]
Yang, Cheng [1 ]
机构
[1] Jiangnan Univ, Sch Chem & Mat Engn, Key Lab Synthet & Biol Colloids, Minist Educ, Wuxi 214122, Peoples R China
[2] Jiangnan Univ, Int Joint Res Ctr Photorespons Mol & Mat, Sch Chem & Mat Engn, Wuxi 214122, Peoples R China
关键词
PREMATURE SENESCENCE; DOXORUBICIN; ENZYME; PROBES;
D O I
10.1039/d2cc05550c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A near-infrared fluorescent nanoprobe based on semiconducting polymer nanoparticles (SPNs) for the detection of senescence-associated beta-gal (SA-beta-gal) is developed. Benefiting from the intrinsic lysosome-locating feature, this probe can be successfully used for the visualization of SA-beta-gal in living cells.
引用
收藏
页码:2974 / 2977
页数:4
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