Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy

被引：9

作者：

Tan, Mingdian ^{[1
,8
]}

Ge, Yizhi ^{[2
,3
]}

Wang, Xiaogang ^{[4
]}

Wang, Yan ^{[5
,6
]}

Liu, Yi ^{[1
]}

He, Feng ^{[6
]}

Teng, Hongqi ^{[7
]}

机构：

[1] Asian Liver Ctr, Sch Med, Stanford, CA 94305 USA

[2] Nanjing Med Univ, Affiliated Canc Hosp, Jiangsu Canc Hosp, Nanjing, Peoples R China

[3] Jiangsu Inst Canc Res, Nanjing, Peoples R China

[4] Soochow Univ, Affiliated Hosp 3, Changzhou, Peoples R China

[5] Stanford Univ, Stanford Canc Inst, Sch Med, Stanford, CA USA

[6] Stanford Univ, Sch Med, Stanford, CA USA

[7] Univ Texas MD Anderson Canc Ctr, Houston, TX USA

[8] Asian Liver Ctr, Sch Med, Dept Surg, Stanford, CA 94305 USA

来源：

TECHNOLOGY IN CANCER RESEARCH & TREATMENT | 2023年 / 22卷

关键词：

EVs; tumor; drug delivery; CELL-DERIVED EXOSOMES; PROSTATE-CANCER; TGF-BETA; REVEALS; ACTIVATION; BIOMARKERS; MECHANISM; PATHWAY; ANGIOGENESIS; PROGRESSION;

D O I：

10.1177/15330338231171463

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In recent years, extracellular vesicles (EVs) have gained significant attention due to their tremendous potential for clinical applications. EVs play a crucial role in various aspects, including tumorigenesis, drug resistance, immune escape, and reconstruction of the tumor microenvironment. Despite the growing interest in EVs, many questions still need to be addressed before they can be practically applied in clinical settings. This paper aims to review EVs' isolation methods, structure research, the roles of EVs in tumorigenesis and their mechanisms in multiple types of tumors, their potential application in drug delivery, and the expectations for their future in clinical research.

引用

页数：16

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