Long Non-Coding RNA and Chemoresistance in Bladder Cancer - A Mini Review

被引：4

作者：

Braga Lima, Ana Paula ^{[1
]}

da Silva, Glenda Nicioli ^{[1
,2
,3
]}

机构：

[1] Univ Fed Ouro Preto, Programa Posgrad Ciencias Farmaceut CIPHARMA, Ouro Preto, MG, Brazil

[2] Univ Fed Ouro Preto, Programa Posgrad Ciencia Biol CBIOL, Ouro Preto, MG, Brazil

[3] Univ Fed Ouro Preto, Dept Anal Clin DEACL, Escola Farm, Ouro Preto, MG, Brazil

来源：

CANCER INVESTIGATION | 2023年 / 41卷 / 02期

关键词：

Bladder cancer; chemoresistance; lncRNA; CELL-PROLIFERATION; GASTRIC-CANCER; GEMCITABINE-RESISTANCE; PROGNOSTIC BIOMARKER; UROTHELIAL CARCINOMA; CISPLATIN-RESISTANCE; MOLECULAR-MECHANISMS; DRUG-RESISTANCE; DOWN-REGULATION; GHET1; PROMOTES;

D O I：

10.1080/07357907.2022.2146703

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Bladder cancer is the 10th most common cancer worldwide. It is a heterogeneous disease, comprising several tumor subtypes with differences in histology, genomic aberrations, prognosis and sensitivity to anti-cancer treatments. Although the treatment of bladder cancer is based tumor classifications and gradings, patients have different clinical response. In recent years, long non-coding RNAs (lncRNAs) were associated with bladder cancer chemoresistance. Thus, lncRNAs seem to be promising targets in treatment of bladder cancer. This review highlights the recent findings concerning lncRNAs and their relevance to the chemoresistance of bladder cancer. This may provide a basis for exploiting more robust therapeutic approaches in the future.

引用

页码：164 / 172

页数：9

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