"One-Pot" Method Preparation of Dendritic Mesoporous Silica-Loaded Matrine Nanopesticide for Noninvasive Administration Control of Monochamus alternatus: The Vector Insect of Bursapherenchus xylophophilus

被引：1

作者：

Ding, Zhenting ^{[1
]}

Wei, Ke ^{[2
]}

Zhang, Yiwu ^{[1
]}

Ma, Xueli ^{[3
]}

Yang, Liu ^{[1
]}

Zhang, Weiguang ^{[1
]}

Liu, Huixiang ^{[1
]}

Jia, Chunyan ^{[4
]}

Shen, Weixing ^{[4
]}

Ma, Shencheng ^{[4
]}

Xu, Li ^{[4
]}

Zhou, Chenggang ^{[1
]}

Liu, Yanxue ^{[1
]}

Gao, Shangkun ^{[1
]}

Ji, Yingchao ^{[1
]}

机构：

[1] Shandong Agr Univ, Coll Plant Protect, Shandong Forestry Pest Prevent & Control Engn Tech, Tai An 271018, Peoples R China

[2] Chinese Acad Forestry, Ecol & Nat Conservat Inst, Beijing 100091, Peoples R China

[3] Taishan Vocat & Tech Coll, Dept Bioengn, Tai An 271001, Peoples R China

[4] Taishan Scenery & Scen Spot Area Management Comm, Tai An 271000, Peoples R China

来源：

ACS BIOMATERIALS SCIENCE & ENGINEERING | 2024年 / 10卷 / 03期

基金：

中国国家自然科学基金;

关键词：

one-pot"method; matrine nanobiopesticides; noninvasive administration; dendritic mesoporous silica; Monochamus alternatus; NANOPARTICLES; DELIVERY;

D O I：

10.1021/acsbiomaterials.3c01270

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Monochamus alternatus is an important stem-boring pest in forestry. However, the complex living environment of Monochamus alternatus creates a natural barrier to chemical control, resulting in a very limited control effect by traditional insecticidal pesticides. In this study, a stable pesticide dendritic mesoporous silica-loaded matrine nanopesticide (MAT@DMSNs) was designed by encapsulating the plant-derived pesticide matrine (MAT) in dendritic mesoporous silica nanoparticles (DMSNs). The results showed that MAT@DMSNs, sustainable nanobiopesticides with high drug loading capacity (80%) were successfully constructed. The release efficiency of DMSNs at alkaline pH was slightly higher than that at acidic pH, and the cumulative release rate of MAT was about 60% within 25 days. In addition, the study on the toxicity mechanism of MAT@DMSNs showed MAT@DMSNs were more effective than MAT and MAT (0.3% aqueous solutions) in touch and stomach toxicity, which might be closely related to their good dispersibility and permeability. Furthermore, MAT@DMSNs are also involved in water transport in trees, which can further transport the plant-derived insecticides to the target site and improve its insecticidal effect. Meanwhile, in addition, the use of essential oil bark penetrants in combination with MAT@DMSNs effectively avoids the physical damage to pines caused by traditional trunk injections and the development of new pests and diseases induced by the traditional trunk injection method, which provides a new idea for the application of biopesticides in the control of stem-boring pests in forestry.

引用

页码：1507 / 1516

页数：10