A Rare Case of PL-7-Associated Immune- Mediated Necrotizing Myopathy With Isolated Dysphagia as the Presenting Symptom

被引：0

作者：

Khan, Tahir ^{[1
]}

Shareef, Aleeya ^{[2
]}

Shahid, Mohammad ^{[1
]}

Shabbir, Ehsan ^{[1
]}

Musleh, Mustafa ^{[3
]}

机构：

[1] Premier Miami Valley Hosp, Internal Med, Dayton, OH USA

[2] Wright State Univ, Boonshoft Sch Med, Internal Med, Dayton, OH 45435 USA

[3] Premier Miami Valley Hosp, Gastroenterol, Dayton, OH USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 04期

关键词：

pl; 7; antibodies; anti pl7; proximal muscle weakness; necrotizing autoimmune myopathy (nam); inflammatory myopathy; dysphagia; immune mediated necrotizing myopathy (imnm);

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Immune-mediated necrotizing myopathy (IMNM) is a rare, progressive disease that accounts for about 19% of all inflammatory myopathies. Dysphagia occurs in about 20%-30% of IMNM patients. This case results in the third presumptive instance of IMNM with dysphagia as the initial symptom. Given that isolated dysphagia in IMNM is atypical to the conventional symptoms in the late stage of the disease, it is critical for clinicians to have a high degree of suspicion for IMNM due to the aggressive nature of the disease and its refractoriness to treatment. Additionally, this case also highlights an atypical autoantibody, PL-7, being positive in an IMNM patient who presents with dysphagia as an initial symptom.

引用

页数：4