Perioperative Acute Kidney Injury

被引：1

作者：

Goeddel, Lee ^{[1
]}

Akca, Ozan ^{[1
]}

机构：

[1] Johns Hopkins Univ, Dept Anesthesiol & Crit Care Med, Sch Med, Baltimore, MD 21218 USA

来源：

TURKISH JOURNAL OF INTENSIVE CARE-TURK YOGUN BAKIM DERGISI | 2023年 / 21卷 / 03期

关键词：

Perfusion; oxygen; oxygenation; hypoxia; oxygen delivery; blood pressure; hypotension; hemoglobin; acute kidney injury; creatinine; lipocalin (NGAL); hypoxia inducible factor; Kidney Disease: Improving Global Outcomes; INTRAOPERATIVE HYPOTENSION; NONCARDIAC SURGERY; MYOCARDIAL INJURY; INSULIN THERAPY; ASSOCIATION; HYPERCHLOREMIA; BIOMARKERS; PREDICTORS; MORTALITY; OUTCOMES;

D O I：

10.4274/tybd.galenos.2023.23855

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Acute kidney injury (AKI) is one of the important complications of the perioperative period, and associated with increased risk of chronic kidney disease, renal replacement therapy requirements, increased cost, and risk of mortality. In this overview, we summarized baseline confounders and surgical procedure related risk factors contributing to the perioperative AKI, which may serve as risk scores, improve early diagnosis, contribute to prevention, and early management of AKI. There are immediate needs for context specific clinical prediction scores and novel biomarkers to very early diagnose AKI. Preventive guidance provided by Kidney Disease: Improving Global Outcomes is a helpful practical tool for clinicians. Potential roles of novel biomarkers and their context specific contributions require further exploration and close attention. Perioperative hemodynamics and oxygenation appear to contribute to AKI. Therefore, while their optimization can be recommended, their detailed and context specific roles need further explored. Overall, decreased exposure to nephrotoxic agents is recommended to further decrease the impact of perioperative AKI.

引用

页码：153 / 161

页数：9

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