Gut microbiota affects brain development and behavior

被引：10
|
作者：
Kim, Gun-Ha [1 ]
Shim, Jung-Ok [2 ]
机构：
[1] Korea Inst Radiol & Med Sci, Korea Canc Ctr Hosp, Dept Pediat, Div Pediat Neurol, 75 Nowon Ro, Seoul 01812, South Korea
[2] Korea Univ, Coll Med, Dept Pediat, Div Pediat Gastroenterol, Seoul, South Korea
来源：
CLINICAL AND EXPERIMENTAL PEDIATRICS | 2023年 / 66卷 / 07期
关键词：
Gut-brain axis; Microbiota; Autism; Development; Brain; LACTIC-ACID BACTERIA; AUTISM SPECTRUM DISORDER; CHILDREN; ACETYLCHOLINE; EXPRESSION; INFECTION; SYMPTOMS; RECEPTOR; BARRIER; CELLS;
D O I：
10.3345/cep.2021.01550
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
The gut covers a large surface area of the body and faces various external factors. The brain works in concert with commensal microbes in the gut to efficiently process the enormous amount of chemical signals that enter the gut every day. This review discusses: (1) evidence that gut bacteria can alter brain development and behavior, (2) mechanisms by which gut bacteria communicate with the brain, (3) preclinical and clinical studies demonstrating the impact of gut microbiota on autism spectrum disorder, and (4) variables worth consideration by future research on gut bacteria.
引用
收藏
页码：274 / 280
页数：7
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