Tranexamic Acid Use in Pediatric Craniotomies at a Large Tertiary Care Pediatric Hospital: A Five Year Retrospective Study

被引：1

作者：

Wang, Jue T. ^{[1
]}

Seshadri, Samir C. ^{[1
]}

Butler, Carolyn G. ^{[1
]}

Staffa, Steven J. ^{[1
]}

Kordun, Anna S. ^{[1
]}

Lukovits, Karina E. ^{[1
]}

Goobie, Susan M. ^{[1
]}

机构：

[1] Boston Childrens Hosp, Dept Anesthesiol Crit Care & Pain Med, Boston, MA 02115 USA

来源：

JOURNAL OF CLINICAL MEDICINE | 2023年 / 12卷 / 13期

关键词：

pediatrics; neurosurgery; patient blood management (PBM); tranexamic acid; antifibrinolytics; blood loss; INTRAOPERATIVE BLOOD-LOSS; SURGERY; TRANSFUSION; CHILDREN; ANTIFIBRINOLYTICS; EFFICACY; SAFETY;

D O I：

10.3390/jcm12134403

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Tranexamic acid (TXA), a synthetic antifibrinolytic drug, has proven efficacy and is recommended for major pediatric surgery to decrease perioperative blood loss. Accumulating evidence suggests that TXA reduces bleeding and transfusion in a variety of adult neurosurgical settings. However, there is a paucity of research regarding TXA indications for pediatric neurosurgery and thus, there are currently no recommendations for its use with this specific population. The objective of this study is to evaluate the existing practice of TXA administration for pediatric neurosurgery at a U.S. tertiary care pediatric hospital over a five-year period. The authors conclude that TXA administration is feasible and should be considered for pediatric neurosurgical cases where potential blood loss is a concern.

引用

页数：8

共 29 条

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