Review of Postoperative Care for Heart Transplant Recipients

被引:1
作者
Hwang, Nian Chih [1 ,2 ,4 ]
Sivathasan, Cumaraswamy [3 ]
机构
[1] Singapore Gen Hosp, Dept Anaesthesiol, Singapore, Singapore
[2] Natl Heart Ctr, Dept Cardiothorac Anesthesia, Dept Cardiothorac Surg, Singapore, Singapore
[3] Natl Heart Ctr, Dept Cardiothorac Surg, Mech Cardiac Support & Heart Transplant Program, Singapore, Singapore
[4] Singapore Gen Hosp, Dept Anaesthesiol, 1 Hosp Dr, Singapore 169608, Singapore
关键词
sinoatrial node dysfunction; pulmonary vascular resistance; primary graft dysfunction; vasoplegia; immunosuppressive therapy; prophylaxis against; infection; INHALED NITRIC-OXIDE; PRIMARY GRAFT DYSFUNCTION; EXTRACORPOREAL MEMBRANE-OXYGENATION; SYSTEMIC VASCULAR-RESISTANCE; RIGHT-VENTRICULAR FAILURE; METHYLENE-BLUE; CARDIAC-SURGERY; RISK-FACTORS; CARDIOPULMONARY BYPASS; VASOPLEGIC SYNDROME;
D O I
10.1053/j.jvca.2022.09.083
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
The early postoperative management strategies after heart transplantation include optimizing the function of the denervated heart, correcting the causes of hemodynamic instability, and initiating and maintaining immunosuppressive therapy, allograft rejection surveillance, and prophylaxis against infections caused by immunosuppression. The course of postoperative support is influenced by the quality of allograft myocardial protec-tion prior to implantation and reperfusion, donor-recipient heart size matching, surgical technique of orthotopic heart transplantation, and patient factors (eg, preoperative condition, immunologic compatibility, postoperative vasomotor tone, severity and reversibility of pulmonary vascular hypertension, pulmonary function, mediastinal blood loss, and end-organ perfusion). This review provides an overview of the early postoperative care of recipients and includes a brief description of the surgical techniques for orthotopic heart transplantation.(c) 2022 Elsevier Inc. All rights reserved.
引用
收藏
页码:112 / 126
页数:15
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