Sustained Efficacy and Safety with Asciminib (ASC) after Almost 4 Years of Median Followup from Ascembl, a Phase 3 Study of ASC Vs Bosutinib (BOS) in Patients (Pts) with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) after ≥2 Prior Tyrosine Kinase Inhibitors (TKIs): An End of Study Treatment (EOS Tx) Update, Including Results from Switch Population

被引：8

作者：

Mauro, Michael ^{[1
]}

Minami, Yosuke ^{[2
]}

Hochhaus, Andreas ^{[3
]}

Lomaia, Elza ^{[4
]}

Voloshin, Sergei ^{[5
]}

Turkina, Anna ^{[6
]}

Kim, Dong-Wook ^{[7
]}

Apperley, Jane F. ^{[8
]}

Cortes, Jorge ^{[9
]}

Abdo, Andre N. R. ^{[10
]}

Fogliatto, Laura Maria ^{[11
]}

Kim, Dennis Dong Hwan ^{[12
]}

le Coutre, Philipp ^{[13
]}

Saussele, Susanne ^{[14
]}

Annunziata, Mario ^{[15
]}

Hughes, Timothy P. ^{[16
]}

Chaudhri, Naeem A. ^{[17
]}

Chee, Lynette C. Y. ^{[18
,19
]}

Gutierrez, Valentin Garcia ^{[20
]}

Sasaki, Koji ^{[21
]}

Freitas, Carla Maria Boquimpani De Moura ^{[22
]}

Kapoor, Shruti ^{[23
]}

Espurz, Noemi ^{[24
]}

Dhamal, Vishal ^{[25
]}

Rea, Delphine ^{[26
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, New York, NY USA

[2] Natl Canc Ctr Hosp East, Kashiwa, Chiba, Japan

[3] Univ Klinikum Jena, Jena, Germany

[4] Almazov Natl Med Res Ctr, St Petersburg, Russia

[5] Russian Sci & Res Inst Hematol & Transfusiol, St Petersburg, Russia

[6] Natl Med Res Ctr Hematol, Moscow, Russia

[7] Uijeongbu Eulji Med Ctr, Uijeoungbu Si, South Korea

[8] Imperial Coll London, Ctr Haematol, London, England

[9] Augusta Univ, Georgia Canc Ctr, Augusta, GA USA

[10] Inst Canc Estado Sao Paulo ICESPSP, Sao Paulo, Brazil

[11] Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil

[12] Univ Hlth Network, Princess Margaret Canc Ctr, Toronto, ON, Canada

[13] Charite Univ Med Berlin, Berlin, Germany

[14] Heidelberg Univ, Med Fak Mannheim, Med Klin 3, Mannheim, Germany

[15] AORN Cardarelli, Div Hematol, Naples, Italy

[16] South Australian Hlth & Med Res Inst SAHMRI, Adelaide, SA, Australia

[17] KFSHRC, Dept Hematol Stem Cell Transplantat & Cellular Th, Riyadh, Saudi Arabia

[18] Royal Melbourne Hosp, Dept Clin Haematol, Parkville, Vic, Australia

[19] Royal Melbourne Hosp, Bone Marrow Transplant Serv, Parkville, Vic, Australia

[20] Hosp Univ Ramon & Cajal IRYCIS, Serv Hematol, Madrid, Spain

[21] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX USA

[22] State Inst Hematol Arthur Siquiera Cavalcanti, HEMORIO, Rio De Janeiro, RJ, Brazil

[23] Novartis Pharmaceut, E Hanover, NJ USA

[24] Novartis Pharma AG, Basel, Switzerland

[25] Novartis Healthcare Private Ltd, Hyderabad, India

[26] Hop St Louis, Dept Hematol, Paris, France

来源：

BLOOD | 2023年 / 142卷

关键词：

D O I：

10.1182/blood-2023-186854

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：6