Current management of uveal melanoma: A review

被引：25

作者：

Bai, Haixia ^{[1
]}

Bosch, Jacobus J. ^{[2
,3
]}

Heindl, Ludwig M. ^{[4
,5
,6
]}

机构：

[1] Zhejiang Univ, Affiliated Hosp 2, Eye Ctr, Sch Med, Hangzhou, Peoples R China

[2] Ctr Human Drug Res, Leiden, Netherlands

[3] Leiden Univ, Med Ctr, Leiden, Netherlands

[4] Univ Cologne, Fac Med, Dept Ophthalmol, Kerpener Str 62, D-50937 Cologne, Germany

[5] Univ Hosp Cologne, Kerpener Str 62, D-50937 Cologne, Germany

[6] Ctr Integrated Oncol CIO Aachen Bonn Cologne Duess, Cologne, Germany

来源：

CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY | 2023年 / 51卷 / 05期

关键词：

eye tumour; immunotherapy; metastasis; radiotherapy; uveal melanoma; COMS RANDOMIZED-TRIAL; PRIMARY TRANSPUPILLARY THERMOTHERAPY; COLLABORATIVE OCULAR MELANOMA; PROTON-BEAM THERAPY; CHOROIDAL MELANOMA; IRIS MELANOMA; LAMELLAR SCLEROUVECTOMY; PLAQUE RADIOTHERAPY; RADIATION-THERAPY; CILIARY BODY;

D O I：

10.1111/ceo.14214

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Uveal melanoma is the most frequent primary intraocular cancer in adulthood and is mostly localised to the choroid. It can be treated using radiation therapy, laser therapy, local resection and enucleation, with the best results achieved by combining these procedures. However, up to half of patients develop metastatic disease. There are no efficacious treatment methods for patients in advanced stage or with metastasis. In recent years, several novel treatment modalities aimed at improving tumour control and reducing adverse events have emerged. This review summarises current clinical treatment methods and new therapeutic perspectives for uveal melanoma.

引用

页码：484 / 494

页数：11

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