Trauma-related falls in an urban geriatric population: predictive risk factors for poorer clinical outcomes

被引:5
作者
Farrell, Alexander [1 ]
Castro, Taylor [2 ]
Nalubola, Shreya [3 ]
Lakhi, Nisha [3 ,4 ]
机构
[1] Touro Univ, Coll Osteopath Med, Middletown, NY USA
[2] New York Inst Technol, Coll Osteopath Med, Old Westbury, NY USA
[3] New York Med Coll, Sch Med, Valhalla, NY 10595 USA
[4] Richmond Univ, Med Ctr, Dept Trauma Surg, Staten Isl, NY 10310 USA
关键词
Elderly; Falls; Polypharmacy; Risk factors; Adverse outcome; Trauma; FUNCTIONAL IMPAIRMENTS; POLYPHARMACY; FRAILTY; ADULTS; AGE;
D O I
10.1186/s40621-023-00418-9
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
BackgroundThe aim of this study was to elucidate associations between polypharmacy, types of medications, and geriatric comorbidities to identify predictive risk factors for poorer clinical outcomes following trauma-related falls in the geriatric population. Nearly 80% of trauma-related hospital admissions in the older adult population are secondary to falls, accounting for 3 million emergency department visits annually. Numerous studies have demonstrated associations between falls, polypharmacy, and other geriatric comorbidities, but studies outlining predictive risk factors for poor clinical outcomes are lacking.MethodsA retrospective cohort study of 1087 patients >= 65 years old who presented to Level 1 Trauma Center after a trauma-related fall. Comorbidities, current medication, demographic information, and clinical outcomes were identified to ascertain predictive risk factors for poorer clinical outcomes. Variables were assessed for statistical significance on unadjusted analysis. Variables found to be significant were entered into a multivariable logistic regression model to test for adjusted associations, with p < 0.05 as statistically significant, and presented as adjusted odds ratios with 95% confidence intervals.ResultsPolypharmacy >= 4 medications (aOR 2.38 (1.10-5.15), p < .028) was an independent predictor of hospital readmission within 30 days. Chronic kidney disease, male gender, and Asian race had an increased association with ICU admission. History of malignancy (aOR 3.65 (1.62-8.19), p < .002) and chronic kidney disease (aOR 2.56 (1.11-5.96), p < .027) were independent predictors of 30-day mortality.ConclusionsPolypharmacy, chronic renal disease, malignancy history, male gender, and Asian race had an increased association of adverse clinical outcomes after falls in the geriatric population. Critical evaluation of patients with these risk factors may be needed to mitigate risk in this population.
引用
收藏
页数:11
相关论文
共 37 条
[11]  
Frazier Susan C, 2005, J Gerontol Nurs, V31, P4
[12]   Medication Use and Associated Risk of Falling in a Geriatric Outpatient Population [J].
Freeland, Kathryn N. ;
Thompson, Amy N. ;
Zhao, Yumin ;
Leal, Julie E. ;
Mauldin, Patrick D. ;
Moran, William P. .
ANNALS OF PHARMACOTHERAPY, 2012, 46 (09) :1188-1192
[13]   Frailty in older adults: Evidence for a phenotype [J].
Fried, LP ;
Tangen, CM ;
Walston, J ;
Newman, AB ;
Hirsch, C ;
Gottdiener, J ;
Seeman, T ;
Tracy, R ;
Kop, WJ ;
Burke, G ;
McBurnie, MA .
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2001, 56 (03) :M146-M156
[14]  
Fuller GF, 2000, AM FAM PHYSICIAN, V61, P2159
[15]   Falls and functional impairments in cancer survivors with chemotherapy-induced peripheral neuropathy (CIPN): a University of Rochester CCOP study [J].
Gewandter, J. S. ;
Fan, L. ;
Magnuson, A. ;
Mustian, K. ;
Peppone, L. ;
Heckler, C. ;
Hopkins, J. ;
Tejani, M. ;
Morrow, G. R. ;
Mohile, S. G. .
SUPPORTIVE CARE IN CANCER, 2013, 21 (07) :2059-2066
[16]   The association between chronic kidney disease, falls, and fractures: a systematic review and meta-analysis [J].
Goto, N. A. ;
Weststrate, A. C. G. ;
Oosterlaan, F. M. ;
Verhaar, M. C. ;
Willems, H. C. ;
Emmelot-Vonk, M. H. ;
Hamaker, M. E. .
OSTEOPOROSIS INTERNATIONAL, 2020, 31 (01) :13-29
[17]   Measuring Aging and Identifying Aging Phenotypes in Cancer Survivors [J].
Guida, Jennifer L. ;
Ahles, Tim A. ;
Belsky, Daniel ;
Campisi, Judith ;
Cohen, Harvey Jay ;
DeGregori, James ;
Fuldner, Rebecca ;
Ferrucci, Luigi ;
Gallicchio, Lisa ;
Gavrilov, Leonid ;
Gavrilova, Natalia ;
Green, Paige A. ;
Jhappan, Chamelli ;
Kohanski, Ronald ;
Krull, Kevin ;
Mandelblatt, Jeanne ;
Ness, Kirsten K. ;
O'Mara, Ann ;
Price, Nathan ;
Schrack, Jennifer ;
Studenski, Stephanie ;
Theou, Olga ;
Tracy, Russell P. ;
Hurria, Arti .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2019, 111 (12) :1245-1254
[18]  
Izzo JL Jr, 2011, POL ARCH MED WEWN, V121, P303
[19]   Fall-induced deaths among elderly people [J].
Kannus, P ;
Parkkari, J ;
Niemi, S ;
Palvanen, M .
AMERICAN JOURNAL OF PUBLIC HEALTH, 2005, 95 (03) :422-424
[20]   Characteristics of fall-related head injury versus non-head injury in the older adults [J].
Kim, Sun Hyu ;
Kim, Sunpyo ;
Cho, Gyu Chong ;
Lee, Ji Hwan ;
Park, Eun Jung ;
Lee, Duk Hee .
BMC GERIATRICS, 2021, 21 (01)