Thymic Carcinoid in a Patient with Concurrent Manifestations of Multiple Endocrine Neoplasia Type 1

被引:0
作者
Zhu, Jasmine [1 ,2 ]
Dean, Samantha [3 ]
Hafeez, Umbreen [2 ,3 ,4 ]
Neoh, Sandra [1 ]
机构
[1] Austin Hlth, Dept Endocrinol, 145 Studley Rd, Heidelberg, Vic 3084, Australia
[2] Univ Melbourne, Melbourne Med Sch, Parkville, Vic 3010, Australia
[3] Austin Hlth, Dept Oncol, 145 Studley Rd, Heidelberg, Vic 3084, Australia
[4] La Trobe Univ, Sch Canc Med, Plenty Rd & Kingsbury Dr, Bundoora, Vic 3086, Australia
关键词
SURVIVAL; TUMORS;
D O I
10.1155/2023/8801080
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Thymic carcinoid tumours, especially in the context of multiple endocrine neoplasia type 1 (MEN 1), present significant clinical challenges due to their rarity and aggressive nature. This case report describes a complex patient with MEN 1, who suffered from multiple manifestations of the disease, including thymic carcinoid. The tumour was initially resected and treated with adjuvant radiotherapy. Due to slow progression over the years, the tumour was treated with two lines of chemotherapy before the patient succumbed to progressive disease. There is currently limited evidence favoring any specific medical treatment for thymic carcinoid.
引用
收藏
页数:5
相关论文
共 12 条
  • [1] Clinical Features, Treatments, and Outcomes of Patients with Thymic Carcinoids and Multiple Endocrine Neoplasia Type 1 Syndrome at MD Anderson Cancer Center
    Christakis, Ioannis
    Qiu, Wei
    Figueroa, Angelica M. Silva
    Hyde, Samuel
    Cote, Gilbert J.
    Busaidy, Naifa L.
    Williams, Michelle
    Grubbs, Elizabeth
    Lee, Jeffrey E.
    Perrier, Nancy D.
    [J]. HORMONES & CANCER, 2016, 7 (04): : 279 - 287
  • [2] Treatment, prognostic markers and survival in thymic neuroendocrine tumours. A study from a single tertiary referral centre
    Crona, Joakim
    Bjorklund, Peyman
    Welin, Staffan
    Kozlovacki, Gordana
    Oberg, Kjell
    Granberg, Dan
    [J]. LUNG CANCER, 2013, 79 (03) : 289 - 293
  • [3] Natural Course and Survival of Neuroendocrine Tumors of Thymus and Lung in MEN1 Patients
    de Laat, Joanne M.
    Pieterman, Carolina R.
    van den Broek, Medard F.
    Twisk, Jos W.
    Hermus, Ad R.
    Dekkers, Olaf M.
    de Herder, Wouter W.
    van der Horst-Schrivers, Anouk N.
    Drent, Madeleine L.
    Bisschop, Peter H.
    Havekes, Bas
    Vriens, Menno R.
    Valk, Gerlof D.
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2014, 99 (09) : 3325 - 3333
  • [4] Thymomas and Thymic Carcinomas Clinical Practice Guidelines in Oncology
    Ettinger, David S.
    Riely, Gregory J.
    Akerley, Wallace
    Borghaei, Hossein
    Chang, Andrew C.
    Cheney, Richard T.
    Chirieac, Lucian R.
    D'Amico, Thomas A.
    Demmy, Todd L.
    Govindan, Ramaswamy
    Grannis, Frederic W., Jr.
    Grant, Stefan C.
    Horn, Leora
    Jahan, Thierry M.
    Komaki, Ritsuko
    Kong, Feng-Ming
    Kris, Mark G.
    Krug, Lee M.
    Lackner, Rudy P.
    Lennes, Inga T.
    Loo, Billy W., Jr.
    Martins, Renato
    Otterson, Gregory A.
    Patel, Jyoti D.
    Pinder-Schenck, Mary C.
    Pisters, Katherine M.
    Reckamp, Karen
    Rohren, Eric
    Shapiro, Theresa A.
    Swanson, Scott J.
    Tauer, Kurt
    Wood, Douglas E.
    Yang, Stephen C.
    Gregory, Kristina
    Hughes, Miranda
    [J]. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2013, 11 (05): : 562 - 576
  • [5] Thymic Neuroendocrine Tumors in Multiple Endocrine Neoplasia Type 1: A Comparative Study on 21 Cases Among a Series of 761 MEN1 from the GTE (Groupe des Tumeurs Endocrines)
    Goudet, Pierre
    Murat, Arnaud
    Cardot-Bauters, Catherine
    Emy, Philippe
    Baudin, Eric
    Choplin, Helene du Boullay
    Chapuis, Yves
    Kraimps, Jean-Louis
    Sadoul, Jean-Louis
    Tabarin, Antoine
    Verges, Bruno
    Carnaille, Bruno
    Niccoli-Sire, Patricia
    Costa, Annie
    Calender, Alain
    [J]. WORLD JOURNAL OF SURGERY, 2009, 33 (06) : 1197 - 1207
  • [6] Acromegaly and Cushing's syndrome due to ectopic production of GHRH and ACTH by a thymic carcinoid tumour:: in vitro responses to GHRH and GHRP-6
    Jansson, JO
    Svensson, J
    Bengtsson, BÅ
    Frohman, LA
    Ahlman, H
    Wängberg, B
    Nilsson, O
    Nilsson, M
    [J]. CLINICAL ENDOCRINOLOGY, 1998, 48 (02) : 243 - 250
  • [7] Thymic Neuroendocrine Neoplasms: Biological Behaviour and Therapy
    Jia, Ru
    Sulentic, Petra
    Xu, Jian-Ming
    Grossman, Ashley B.
    [J]. NEUROENDOCRINOLOGY, 2017, 105 (02) : 105 - 114
  • [8] Long-term effect of everolimus in recurrent thymic neuroendocrine neoplasia
    Lang, Matthias
    Hackert, Thilo
    Anamaterou, Chrysanthi
    [J]. CLINICAL ENDOCRINOLOGY, 2021, 95 (05) : 744 - 751
  • [9] Multiple endocrine neoplasia type 1
    Marini, Francesca
    Falchetti, Alberto
    Del Monte, Francesca
    Sala, Silvia Carbonell
    Gozzini, Alessia
    Luzi, Ettore
    Brandi, Maria Luisa
    [J]. ORPHANET JOURNAL OF RARE DISEASES, 2006, 1 (1)
  • [10] The 2015 World Health Organization Classification of Tumors of the Thymus Continuity and Changes
    Marx, Alexander
    Chan, John K. C.
    Coindre, Jean-Michel
    Detterbeck, Frank
    Girard, Nicolas
    Harris, Nancy L.
    Jaffe, Elaine S.
    Kurrer, Michael O.
    Marom, Edith M.
    Moreira, Andre L.
    Mukai, Kiyoshi
    Orazi, Attilio
    Stroebel, Philipp
    [J]. JOURNAL OF THORACIC ONCOLOGY, 2015, 10 (10) : 1383 - 1395