Diastereoselective Synthesis of Pyrazolo[1,2-a][1,2,4]triazine Derivatives via Cross-1,3-dipolar Cyclizations of Azaoxyallyl Cations with N,N' -Cyclic Azomethine Imines

被引：3

作者：

Wang, Gang ^{[1
]}

Wu, Jiang ^{[1
]}

Li, Yi ^{[1
]}

Huang, Zicheng ^{[1
]}

Zou, Jing ^{[1
]}

He, Zhao-Lin ^{[1
]}

机构：

[1] Wuhan Inst Technol, Engn Res Ctr Phosphorus Resources Dev & Utilizat, Sch Chem & Environm Engn, Key Lab Green Chem Engn,Minist Educ,Hubei Key Lab, LiuFang Campus,206 Guanggu 1st Rd, Wuhan 430025, Peoples R China

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 26卷 / 34期

基金：

中国国家自然科学基金;

关键词：

azaoxyallyl cations; cross-1,3-dipolar cyclizations; N; N'-cyclic azomethine imines; diastereoselective synthesis; CATALYZED 3+3 CYCLOADDITION; BENZYL AZOMETHINE YLIDE; FACILE ACCESS; 1,3-DIPOLAR CYCLOADDITION; IMINES; ANNULATION;

D O I：

10.1002/ejoc.202300450

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A cross-1,3-dipolar cycloaddition reaction of a-halohydroxamates (in situ generated azaoxyallyl cations) with N,N'-cyclic azomethine imines was developed. The synthetic protocol provided facile and rapid access to pyrazolo[1,2-a][1,2,4]triazine derivatives in good yields and excellent diastereoselectivities under mild metal-free conditions.

引用

页数：5

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