Air trapping in small airway diseases: A review of imaging technique and findings with an overview of small airway diseases

Air trapping is a common finding radiologists encounter on CT imaging of the thorax. This term is used when there are geographic areas of differing attenuation within the lung parenchyma. Most commonly, this is the result of abnormal retention of air due to complete or partial airway obstruction from small airway pathologies. Perfusional differences due to underlying vascular diseases could also result in these appearances, and hence, inspiratory and full expiratory phase CT studies are required to accurately diagnose air trapping. It is important to note that this can occasionally be present in healthy patients. Multiple diseases are associated with air trapping. Determining the aetiology relies on accurate patient history and concomitant findings on CT. There is currently no consensus on accurate assessment of the severity of air trapping. The ratio of mean lung density between expiration and inspiration on CT and the change in lung volume have demonstrated a positive correlation with the presence of small airway disease. Treatment and resultant patient outcome depend on the underlying aetiology, and hence, radiologists need to be familiar with the common causes of air trapping. This paper outlines the most common disease processes leading to air trapping, including Constrictive bronchiolitis, Hypersensitivity pneumonitis, DIPNECH, and Post-infectious (Swyer-James/Macleod). Various diseases result in the air trapping pattern seen on the expiratory phase CT scan of the thorax. Combining patient history with other concomitant imaging findings is essential for accurate diagnosis and to further guide management.