β-Enaminones from cyclohexane-1,3-diones: Versatile precursors for nitrogen and oxygen-containing heterocycles synthesis

被引:4
作者
Sharma, Dharminder [1 ,6 ]
Kumar, Manish [2 ]
Kumar, Sandeep [3 ]
Bhattacherjee, Dhananjay [4 ]
Shil, Arun Kumar [4 ]
Mehta, Megha [5 ]
Das, Pralay [4 ,7 ]
机构
[1] Jagdish Chandra DAV Coll, Dept Chem, Dasuya, India
[2] Swami Vivekanand Govt Coll, Dept Chem, Ghumarwin, India
[3] Lovely Profess Univ, Dept Chem, Phagwara, India
[4] Inst Himalayan Bioresource Technol, Chem Technol Dept, CSIR, Palampur, India
[5] Jagdish Chandra DAV Coll, Dept Zool, Dasuya, India
[6] Jagdish Chandra DAV Coll, Dept Chem, Dasuya 144205, Punjab, India
[7] Inst Himalayan Bioresource Technol, Chem Technol Dept, CSIR, Palampur 176061, Himachal Prades, India
关键词
Acridine-1; cyclohexane-1; dihydropyridine; 3-dione; 8-dione; beta-enaminones; xanthenes; EFFICIENT ONE-POT; CATALYZED SYNTHESIS; DERIVATIVES; ACRIDINEDIONES; SOLVENT; FACILE; ACID; CYCLOADDITION; ANNULATION; ALCOHOLS;
D O I
10.1080/00397911.2023.2203325
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
beta-Enaminones derived from cyclohexane-1,3-diones reveal a vast variety of bioactivities including anticonvulsant, anti-inflammatory, analgesic, etc. Further, these beta-Enaminones are versatile precursors for the synthesis of several other important heterocycles that illustrates antimicrobial, antibacterial, antifungal, antitumor, calcium channel antagonist, cardiovascular, antiviral activities, etc. Recently, reactions of various beta-enaminones with their counterpart for example aldehydes, Meldrum's acid, N-arylitaconimides, malononitriles, cyanoacetamide, arylglyoxals, ortho-hydroxybenzyl alcohols, o-hydroxystyrenes, and acenaphthoquinone have been recognized for the synthesis of different nitrogen and oxygen heterocycles involving 2-quinolone, 1,4-dihydropyridine, acridine-1,8-dione, indoles, xanthenes, chromenones, etc. These significances of beta-enaminones enthused us to assemble all newly developed methods for the creation of important nitrogen and oxygen-containing heterocycles, which are the chief attraction of this review article.
引用
收藏
页码:953 / 993
页数:41
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