Hyperinflation and its association with successful transition to home ventilator devices in infants with chronic respiratory failure and severe bronchopulmonary dysplasia

被引:3
|
作者
Lagoski, Megan [1 ,2 ]
Reisfeld, Michael [1 ,2 ]
Carpenter, Ryan J. [1 ,2 ]
Lamorena, Emilee [1 ,2 ]
Goodman, Denise M. [1 ,2 ]
Murthy, Karna [1 ,2 ,3 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA
[2] Ann & Robert H Lurie Childrens Hosp Chicago, Chicago, IL 60611 USA
[3] Childrens Hosp Neonatal Consortium, Dover, DE USA
关键词
ASYNCHRONIES; OUTCOMES; IMPACT; BORN; CARE;
D O I
10.1038/s41372-022-01575-3
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
OBJECTIVE: To estimate the association between lung hyperinflation and the time to successful transition to home ventilators in infants with sBPD and chronic respiratory failure. DESIGN/METHODS: Infants with sBPD ResultsSixty-two infants were included; 26 (42%) were hyperinflated. Eleven died before transition, and 51 successfully transitioned. Hyperinflation was associated with both mortality (31% vs 8.3%, p = 0.02) and an increased duration (72 vs. 56 days) to successful transition (hazard ratio (HR) = 0.38, 95% CI: 0.19, 0.76, p = 0.006). Growth velocity was similar after tracheostomy placement. CONCLUSIONS: In infants with chronic respiratory failure and sBPD < 32 weeks' gestation, hyperinflation is related to mortality and inpatient morbidities.
引用
收藏
页码:332 / 336
页数:5
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