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Hyperinflation and its association with successful transition to home ventilator devices in infants with chronic respiratory failure and severe bronchopulmonary dysplasia
被引:3
|作者:
Lagoski, Megan
[1
,2
]
Reisfeld, Michael
[1
,2
]
Carpenter, Ryan J.
[1
,2
]
Lamorena, Emilee
[1
,2
]
Goodman, Denise M.
[1
,2
]
Murthy, Karna
[1
,2
,3
]
机构:
[1] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA
[2] Ann & Robert H Lurie Childrens Hosp Chicago, Chicago, IL 60611 USA
[3] Childrens Hosp Neonatal Consortium, Dover, DE USA
关键词:
ASYNCHRONIES;
OUTCOMES;
IMPACT;
BORN;
CARE;
D O I:
10.1038/s41372-022-01575-3
中图分类号:
R71 [妇产科学];
学科分类号:
100211 ;
摘要:
OBJECTIVE: To estimate the association between lung hyperinflation and the time to successful transition to home ventilators in infants with sBPD and chronic respiratory failure. DESIGN/METHODS: Infants with sBPD ResultsSixty-two infants were included; 26 (42%) were hyperinflated. Eleven died before transition, and 51 successfully transitioned. Hyperinflation was associated with both mortality (31% vs 8.3%, p = 0.02) and an increased duration (72 vs. 56 days) to successful transition (hazard ratio (HR) = 0.38, 95% CI: 0.19, 0.76, p = 0.006). Growth velocity was similar after tracheostomy placement. CONCLUSIONS: In infants with chronic respiratory failure and sBPD < 32 weeks' gestation, hyperinflation is related to mortality and inpatient morbidities.
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页码:332 / 336
页数:5
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