Organoids as an in vitro model to study human tumors and bacteria

被引:0
作者
Liu, Naiyu [1 ]
Liu, Shuxi [1 ]
Xu, Xiaoyue [1 ]
Nong, Xianxian [1 ]
Chen, Hong [1 ]
机构
[1] Guangxi Med Univ, Dept Obstet & Gynecol, Affiliated Hosp 1, Nanning 530000, Peoples R China
关键词
bacteria; organoids; tumor microenvironment; tumor models; tumors; PATIENT-DERIVED ORGANOIDS; SQUAMOUS-CELL CARCINOMA; GUT MICROBIOTA; STEM-CELLS; CANCER; THERAPY; MICROENVIRONMENT; TUMORIGENESIS; ESTABLISHMENT; MANIPULATION;
D O I
10.1002/jso.27626
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Organoids faithfully replicate the morphological structure, physiological functions, stable phenotype of the source tissue. Recent research indicates that bacteria can significantly influence the initiation, advancement, and treatment of tumors. This article provides a comprehensive review of the applications of organoid technology in tumor research, the relationship between bacteria and the genesis and development of tumors, and the exploration of the impact of bacteria on tumors and their applications in research.
引用
收藏
页码:1390 / 1400
页数:11
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