A case of hypertensive emergency with alveolar hemorrhage and thrombotic microangiopathy

被引：0

作者：

Ubara, Yoshifumi ^{[1
,2
]}

Kurihara, Shigekazu ^{[1
,2
]}

Tsuchiya, Yoshiki ^{[3
]}

Oba, Yuki ^{[1
,2
]}

Ikuma, Daisuke ^{[1
,2
]}

Mizuno, Hiroki ^{[1
,2
]}

Yamanouchi, Masayuki ^{[1
,2
]}

Suwabe, Tatsuya ^{[1
,2
]}

Imase, Atsuko ^{[3
]}

Shibata, Nobumitsu ^{[3
]}

Kono, Kei ^{[4
]}

Kinowaki, Keiichi ^{[4
]}

Ohashi, Kenichi ^{[4
,5
]}

Ogata, Kentaro ^{[6
]}

Sawa, Naoki ^{[1
,2
]}

机构：

[1] Toranomon Hosp Kajigaya, Nephrol Ctr, 1-3-1,Takatsu, Kawasaki, Kanagawa 2120015, Japan

[2] Toranomon Gen Hosp, Okinaka Mem Inst Med Res, Tokyo, Japan

[3] Tokatsu Hosp, Dept Urol, Chiba, Japan

[4] Toranomon Gen Hosp, Dept Pathol, Tokyo, Japan

[5] Tokyo Med Dent Univ, Dept Human Pathol, Tokyo, Japan

[6] Tachikawa Hosp, Dept Pathol, Tokyo, Japan

来源：

CEN CASE REPORTS | 2024年 / 13卷 / 06期

关键词：

Thrombotic microangiopathy; Malignant hypertension; Malignant nephrosclerosis; Hemolytic uremic syndrome; PROTEINURIA; PATIENT;

D O I：

10.1007/s13730-024-00863-5

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A 28-year-old woman with a 5-year history of untreated hypertension was admitted for respiratory distress, hemoptysis, and retinopathy. Computed tomography showed diffuse plaques in both lung fields. Acute kidney injury, hemolytic anemia, and thrombocytopenia were noted. Kidney biopsy showed thrombosis with fibrinoid necrosis and edematous intimal thickening and luminal narrowing of the small renal artery, indicating thrombotic microangiopathy; the majority of glomeruli were collapsed. After 8 weeks of treatment with antihypertensive drugs, serum creatinine decreased to 1.0 mg/dL, and the patient recovered. In the absence of any other underlying disease, malignant nephrosclerosis associated with a hypertensive emergency was diagnosed.

引用

页码：450 / 456

页数：7

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