Rice Malt: A Solvent-Catalyst for the Synthesis of N-Substituted Pyrroles

被引：1

作者：

Yadav, Ram Naresh ^{[1
]}

Rohand, Taoufik ^{[2
]}

Banik, Bimal Krishna ^{[3
]}

机构：

[1] Veer Bahadur Singh Purvanchal Univ, Fac Engn & Technol, Dept Chem, Jaunpur 222003, Uttar Pradesh, India

[2] Univ Cadi Ayyad, Fac Polydisciplinaire Safi, Dept Chem, Lab Analyt & Mol Chem, Sidi Bouzid 46000, Safi, Morocco

[3] Prince Mohammad Bin Fahd Univ, Coll Sci & Human Studies, Dept Math & Nat Sci, Deanship Res, Al Khobar, Saudi Arabia

来源：

CURRENT ORGANOCATALYSIS | 2023年 / 10卷 / 04期

基金：

美国国家卫生研究院;

关键词：

Rice malt; polysaccharides; polyhydroxy-sugar; paal-knorr; pyrrole; chemotherapeutics; hexane-2,5-dione; amine; cyclodehydration; cyclo-condensation; aromatization; PAAL-KNORR SYNTHESIS; POLYSUBSTITUTED PYRROLES; EFFICIENT;

D O I：

10.2174/2213337210666230516151722

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Aim: The synthesis of diverse N-substituted pyrroles utilizing rice malt is identified. The reaction of hexane-2,5-dione with various primary amines develops the intriguing pyrrole scaffold in moderate to good yields.Methods: The reaction was carried out at room to ambient temperature in an extremely environmentally benign condition, without the need for any additional solvents or catalysts.Results: In the synthesis of N-derivatized pyrroles, several 1 amines, both cyclic and acyclic residue, have been accomplished.Conclusion: To the best of my knowledge, no study has been reported so far based on Paal-Knorr pyrrole synthesis utilizing rice malt as a catalyst and solvent.

引用

页码：276 / 282

页数：7

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