Roles of interferon induced protein with tetratricopeptide repeats (IFIT) family in autoimmune disease

被引：8
|
作者：
Wu, Yuan-Yuan [1 ]
Xing, Jun [5 ]
Li, Xiao-Feng [2 ,3 ,4 ]
Yang, Ying-Li [2 ,3 ,4 ]
Shao, Hua [1 ]
Li, Jun [2 ,3 ,4 ]
机构：
[1] Southeast Univ, Zhong da Hosp, Dept Pharm, 87 Ding Jia Qiao, Nanjing 210009, Peoples R China
[2] Minist Educ, Anhui Inst Innovat Drugs, Key Lab Antiinflammatory & Immune Med, Hefei, Anhui, Peoples R China
[3] Inflammat & Immune Mediated Dis Lab Anhui Prov, Hefei, Anhui, Peoples R China
[4] Anhui Med Univ, Sch Pharm, Hefei, Anhui, Peoples R China
[5] China Med Univ, Shenyang 110122, Peoples R China
来源：
AUTOIMMUNITY REVIEWS | 2023年 / 22卷 / 11期
基金：
中国国家自然科学基金;
关键词：
IFIT family; Autoimmune disease; IFN-I signaling pathway; Diagnostics; Treatment; SYSTEMIC-LUPUS-ERYTHEMATOSUS; CONNECTIVE-TISSUE; GENE; EXPRESSION; BIOMARKERS;
D O I：
10.1016/j.autrev.2023.103453
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Interferon-induced tetrapeptide repeat (IFIT) family proteins are an important component of the antiviral immune response. There are four known members of the human IFIT family, namely IFIT1, IFIT2, IFIT3 and IFIT5. More and more evidence shows that IFIT family members are involved in a variety of pathophysiological processes in vivo, regulate the homeostasis and differentiation of a variety of cells including immune cells, and are closely related to a variety of autoimmune diseases, which is expected to become a new therapeutic target. This review reviews the biological roles of different IFIT proteins in various autoimmune diseases, and highlights the potential use of these molecules as biomarkers and prognostic factors in autoimmune diseases, with a view to providing ideas for exploring the diagnosis and treatment of autoimmune diseases.
引用
收藏
页数：8
相关论文
共 50 条
  • [21] Chicken Interferon-induced Protein with Tetratricopeptide Repeats 5 Antagonizes Replication of RNA Viruses
    Santhakumar, Diwakar
    Rohaim, Mohammed Abdel Mohsen Shahaat
    Hussein, Hussein A.
    Hawes, Pippa
    Ferreira, Helena Lage
    Behboudi, Shahriar
    Iqbal, Munir
    Nair, Venugopal
    Arns, Clarice W.
    Munir, Muhammad
    SCIENTIFIC REPORTS, 2018, 8
  • [22] Interferon Regulatory Factor 8 (IRF8) Impairs Induction of Interferon Induced with Tetratricopeptide Repeat Motif (IFIT) Gene Family Members
    White, Christine L.
    Kessler, Patricia M.
    Dickerman, Benjamin K.
    Ozato, Keiko
    Sen, Ganes C.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 291 (26) : 13535 - 13545
  • [23] Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5
    Katibah, George E.
    Qin, Yidan
    Sidote, David J.
    Yao, Jun
    Lambowitz, Alan M.
    Collins, Kathleen
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (33) : 12025 - 12030
  • [24] In vitro characterization of the antiviral activity of Bat Interferon-Induced protein with tetratricopeptide repeats 5 (bat IFIT5) against bat-associated rabies virus
    Barboza, Camila Mosca
    Zamudio, Raphaela Mello
    Franco, Ana Claudia
    Batista, Helena Beatriz de Carvalho Ruthner
    JOURNAL OF NEUROVIROLOGY, 2025,
  • [25] Interferon-Induced Protein With Multiple Tetratricopeptide Repeats 3 Is Associated With Response to Chemotherapy and Recurrence but Not With Survival
    Popp, Marie Christine
    Klippstein, Maximilian
    Lohneis, Philipp
    Kalinski, Thomas
    Li, Jiahui
    Quaas, Alexander
    Bludau, Marc
    Wang, Zhefang
    Waldschmidt, Dirk
    Kunzmann, Volker
    Damanakis, Alexander
    Gebauer, Florian
    Zhao, Yue
    Bruns, Christiane J.
    Popp, Felix C.
    PANCREAS, 2020, 49 (10) : 1307 - 1314
  • [26] Distinct expression of interferon-induced protein with tetratricopeptide repeats (IFIT) 1/2/3 and other antiviral genes between subsets of dendritic cells induced by dengue virus 2 infection
    Zhang, Jingshu
    Sze, Daniel Man-Yuen
    Yung, Benjamin Yat-Ming
    Tang, Petrus
    Chen, Wei-June
    Chan, Kwok-Hung
    Leung, Polly Hang-Mei
    IMMUNOLOGY, 2016, 148 (04) : 363 - 376
  • [27] Interferon-induced protein with tetratricopeptide repeats 3 may be a key factor in primary biliary cholangitis
    Motoko Sasaki
    Yasunori Sato
    Yasuni Nakanuma
    Scientific Reports, 11
  • [28] Interferon-induced protein with tetratricopeptide repeats 3 may be a key factor in primary biliary cholangitis
    Sasaki, Motoko
    Sato, Yasunori
    Nakanuma, Yasuni
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [29] Broad-spectrum antiviral functions of duck interferon-induced protein with tetratricopeptide repeats (AvIFIT)
    Rong, Enguang
    Hu, Jiaxiang
    Yang, Chenghuai
    Chen, Hualan
    Wang, Zeng
    Liu, Xiaojuan
    Liu, Wenjie
    Lu, Chang
    He, Penghua
    Wang, Xiaoxue
    Chen, Xiaoyun
    Liu, Jinhua
    Li, Ning
    Huang, Yinhua
    DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2018, 84 : 71 - 81
  • [30] Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) accelerates osteoclast formation by regulating signal transducer and activator of transcription 3 (STAT3) signalling
    Xue, Yuanliang
    Zhao, Chuanliang
    Liu, Tao
    BIOENGINEERED, 2022, 13 (02) : 2285 - 2295
12345