Making human eggs in a dish: are we close?

被引：2
作者：
Frost, Emily R. [1 ]
Gilchrist, Robert B. [1 ]
机构：
[1] Univ New South Wales, Fertil & Res Ctr, Sch Clin Med, Discipline Womens Hlth, Sydney, NSW 2052, Australia
来源：
TRENDS IN BIOTECHNOLOGY | 2024年 / 42卷 / 02期
基金：
英国医学研究理事会;
关键词：
IN-VITRO MATURATION; FOLLICLE-STIMULATING-HORMONE; PRIMARY OVARIAN-FOLLICLES; EMBRYONIC STEM-CELLS; PRIMORDIAL FOLLICLES; MOUSE OOCYTES; INVITRO FERTILIZATION; SECONDARY FOLLICLES; MULTISTEP CULTURE; GROWTH;
D O I：
10.1016/j.tibtech.2023.07.007
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
In the space of 50 years, we have seen incredible achievements in human reproductive medicine. With these leaps forward, it is no wonder that there is a major interest in women's reproductive health research, including extension of reproductive lifespan. Substantial effort is currently being made to address this challenge, including from the commercial sector. In vitro gametogenesis (IVG) in mice is a spectacular breakthrough and has the potential to offer hope to women with intractable infertility. However, with such lofty goals, some reflection may be called for: mastering all of the techniques required for complete and safe IVG in women is likely to be extraordinarily difficult.
引用
收藏
页码：168 / 178
页数：11
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