From Gut to Heart: Role of Indole-3-Propionic Acid in HFpEF

被引：1
作者：
Vacca, Antonio [3 ,4 ]
Schiattarella, Gabriele G. [1 ,2 ,3 ,5 ]
机构：
[1] Charite Univ Med Berlin, Deutsch Herzzentrum Charite, Max Rubner Ctr Cardiovasc Metab Renal Res, Berlin, Germany
[2] German Ctr Cardiovasc Res DZHK, Partner Site Berlin, Berlin, Germany
[3] Max Delbruck Ctr Mol Med Helmholtz Assoc, Translat Approaches Heart Failure & Cardiometab Di, Berlin, Germany
[4] Univ Udine, Dept Med, Clin Med, Udine, Italy
[5] Univ Naples Federico II, Dept Adv Biomed Sci, Div Cardiol, Naples, Italy
来源：
CIRCULATION RESEARCH | 2024年 / 134卷 / 04期
基金：
欧洲研究理事会;
关键词：
Editorials; diet; gastrointestinal microbiome; heart failure; inflammation; metabolism; obesity; sirtuins; PRESERVED EJECTION FRACTION; FAILURE;
D O I：
10.1161/CIRCRESAHA.123.323947
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：390 / 392
页数：3
相关论文
共 50 条
  • [21] Antibiotic-driven dysbiosis in early life disrupts indole-3-propionic acid production and exacerbates allergic airway inflammation in adulthood
    Perdijk, Olaf
    Butler, Alana
    Macowan, Matthew
    Chatzis, Roxanne
    Bulanda, Edyta
    Grant, Rhiannon D.
    Harris, Nicola L.
    Wypych, Tomasz P.
    Marsland, Benjamin J.
    IMMUNITY, 2024, 57 (08) : 1939 - 1954.e7
  • [22] Pretreatment with Indole-3-Propionic Acid Attenuates Lipopolysaccharide-Induced Cardiac Dysfunction and Inflammation Through the AhR/ NF-κB/NLRP3 Pathway
    Zhang, Yiqiong
    Li, Shanshan
    Fan, Xiaojuan
    Wu, Yue
    JOURNAL OF INFLAMMATION RESEARCH, 2024, 17 : 5293 - 5309
  • [23] Indole-3-propionic acid, a product of intestinal flora, inhibits the HDAC6/NOX2 signalling and relieves doxorubicin-induced cardiomyocyte damage
    Li, Chunyan
    Chang, Jingling
    Wang, Yueqi
    Pan, Guozhong
    FOLIA MORPHOLOGICA, 2024, 83 (02) : 382 - 390
  • [24] Role of Indole-3-Acetic Acid in NAFLD Amelioration After Sleeve Gastrectomy
    Wang, Yu
    Wang, Geng
    Bai, Jie
    Zhao, Ning
    Wang, Qingbo
    Zhou, Rui
    Li, Gang
    Hu, Chaojie
    Li, Xin
    Tao, Kaixiong
    Xia, Zefeng
    Wang, Guobin
    OBESITY SURGERY, 2021, 31 (07) : 3040 - 3052
  • [25] Habitual consumption of high-fibre bread fortified with bean hulls increased plasma indole-3-propionic concentration and decreased putrescine and deoxycholic acid faecal concentrations in healthy volunteers
    Sayegh, Marietta
    Ni, Qian Qian
    Ranawana, Viren
    Raikos, Vassilios
    Hayward, Nicholas J.
    Hayes, Helen E.
    Duncan, Gary
    Cantlay, Louise
    Farquharson, Freda
    Solvang, Michael
    Horgan, Graham W.
    Louis, Petra
    Russell, Wendy R.
    Clegg, Miriam
    Thies, Frank
    Neacsu, Madalina
    BRITISH JOURNAL OF NUTRITION, 2023, 130 (09) : 1521 - 1536
  • [26] Uncovering the Role of Gut Microbiota in Amino Acid Metabolic Disturbances in Heart Failure Through Metagenomic Analysis
    Hayashi, Tomohiro
    Yamashita, Tomoya
    Takahashi, Tomoya
    Tabata, Tokiko
    Watanabe, Hikaru
    Gotoh, Yasuhiro
    Shinohara, Masakazu
    Kami, Kenjiro
    Tanaka, Hidekazu
    Matsumoto, Kensuke
    Hayashi, Tetsuya
    Yamada, Takuji
    Hirata, Ken-ichi
    FRONTIERS IN CARDIOVASCULAR MEDICINE, 2021, 8
  • [27] Dysregulated amino acid metabolism in heart failure: role of gut microbiome
    Tang, W. H. Wilson
    CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 2023, 26 (02) : 195 - 200
  • [28] Role of the Aryl Hydrocarbon Receptor and Gut Microbiota-Derived Metabolites Indole-3-Acetic Acid in Sulforaphane Alleviates Hepatic Steatosis in Mice
    Xu, Xiuxiu
    Sun, Siyuan
    Liang, Ling
    Lou, Chenxi
    He, Qijin
    Ran, Maojuan
    Zhang, Lu
    Zhang, Jingyue
    Yan, Chen
    Yuan, Hengjie
    Zhou, Lu
    Chen, Xin
    Dai, Xin
    Wang, Bangmao
    Zhang, Jie
    Zhao, Jingwen
    FRONTIERS IN NUTRITION, 2021, 8
  • [29] Exploring the Relationship between Gut Microbiome Composition and Blood Indole-3-acetic Acid in Hemodialysis Patients
    Wu, Ping-Hsun
    Tseng, Yu-Fang
    Liu, Wangta
    Chuang, Yun-Shiuan
    Tai, Chi-Jung
    Tung, Chun-Wei
    Lai, Kean-Yee
    Kuo, Mei-Chuan
    Chiu, Yi-Wen
    Hwang, Shang-Jyh
    Hung, Wei-Chun
    Lin, Yi-Ting
    BIOMEDICINES, 2024, 12 (01)
  • [30] Enhanced propionic acid production from whey lactose with immobilized Propionibacterium acidipropionici and the role of trehalose synthesis in acid tolerance
    Jiang, Ling
    Cui, Huaiyan
    Zhu, Liying
    Hu, Yi
    Xu, Xian
    Li, Shuang
    Huang, He
    GREEN CHEMISTRY, 2015, 17 (01) : 250 - 259
12345