Nonpulmonary Treatments for Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference

被引:8
作者
Valentine, Stacey L. [1 ]
Kudchadkar, Sapna R. [2 ,3 ,4 ]
Ward, Shan [5 ]
Morrow, Brenda M. [6 ]
Nadkarni, Vinay M. [7 ]
Curley, Martha A. Q. [7 ,8 ,9 ]
机构
[1] Univ Massachusetts Childrens, Dept Pediat, Div Pediat Crit Care, Med Ctr, Worcester, MA 01605 USA
[2] Johns Hopkins Univ, Dept Anesthesiol & Crit Care Med, Sch Med, Baltimore, MD USA
[3] Johns Hopkins Univ, Dept Pediat, Sch Med, Baltimore, MD USA
[4] Johns Hopkins Univ, Dept Phys Med & Rehabil, Sch Med, Baltimore, MD USA
[5] Univ Calif San Francisco, Benioff Childrens Hosp San Francisco & Oakland, Dept Pediat, Div Crit Care, San Francisco, CA USA
[6] Univ Cape Town, Dept Paediat & Child Hlth, Cape Town, South Africa
[7] Univ Penn, Perelman Sch Med, Dept Anesthesia & Crit Care Med, Philadelphia, PA USA
[8] Univ Penn, Sch Nursing, Dept Family & Community Hlth, Philadelphia, PA USA
[9] Childrens Hosp Philadelphia, Res Inst, Philadelphia, PA USA
基金
新加坡国家研究基金会;
关键词
children; critical illness; pediatric acute respiratory distress syndrome; sedation; delirium management; neuromuscular blockade; nutrition; fluid management; transfusion; sleep management; and rehabilitation; CRITICALLY-ILL CHILDREN; NEUROMUSCULAR BLOCKING-AGENTS; EXTRACORPOREAL MEMBRANE-OXYGENATION; CRITICAL-CARE TRANSFUSION; INTENSIVE-CARE; EARLY MOBILIZATION; ENTERAL NUTRITION; RBC TRANSFUSIONS; BENZODIAZEPINE WITHDRAWAL; ACTIVE REHABILITATION;
D O I
10.1097/PCC.0000000000003158
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
OBJECTIVES: To provide an updated review of the literature on nonpulmonary treatments for pediatric acute respiratory distress syndrome (PARDS) from the Second Pediatric Acute Lung Injury Consensus Conference. DATA SOURCES: MEDLINE (Ovid), Embase (Elsevier), and CINAHL Complete (EBSCOhost) STUDY SELECTION: Searches were limited to children with PARDS or hypoxic respiratory failure focused on nonpulmonary adjunctive therapies (sedation, delirium management, neuromuscular blockade, nutrition, fluid management, transfusion, sleep management, and rehabilitation). DATA EXTRACTION: Title/abstract review, full-text review, and data extraction using a standardized data collection form. DATA SYNTHESIS: The Grading of Recommendations Assessment, Development, and Evaluation approach was used to identify and summarize evidence and develop recommendations. Twenty-five studies were identified for full-text extraction. Five clinical practice recommendations were generated, related to neuromuscular blockade, nutrition, fluid management, and transfusion. Thirteen good practice statements were generated on the use of sedation, iatrogenic withdrawal syndrome, delirium, sleep management, rehabilitation, and additional information on neuromuscular blockade and nutrition. Three research statements were generated to promote further investigation in nonpulmonary therapies for PARDS. CONCLUSIONS: These recommendations and statements about nonpulmonary treatments in PARDS are intended to promote optimization and consistency of care for patients with PARDS and identify areas of uncertainty requiring further investigation.
引用
收藏
页码:S45 / S60
页数:16
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