Thyroid impairment and male fertility: a narrative review of literature

被引：0

作者：

Anelli, Valentina ^{[1
]}

Gatta, Elisa ^{[1
]}

Pirola, Ilenia ^{[1
]}

Delbarba, Andrea ^{[1
]}

Rotondi, Mario ^{[2
,3
]}

Cappelli, Carlo ^{[1
,4
]}

机构：

[1] Univ Brescia, Dept Clin & Expt Sci, SSD Endocrinol, Azienda Socio Sanit Terr ASST Spedali Civili Bresc, Brescia, Italy

[2] Istituti Clinici Sci Maugeri IRCCS, Lab Endocrine Disruptors, Istituti Clinici Scientif Maugeri IRCCS, Pavia, Italy

[3] Univ Pavia, Dept Internal Med & Therapeut, Pavia, Italy

[4] Univ Brescia, Dept Clin & Expt Sci, SSD Endocrinol, ASST Spedali Civili Brescia, Piazzale Spedali Civili 1, I-25100 Brescia, Italy

来源：

AGING MALE | 2024年 / 27卷 / 01期

关键词：

Male fertility; male infertility; thyroid; hypothyroidism; hyperthyroidism; PITUITARY-TESTICULAR AXIS; UNITED-STATES POPULATION; MALE-INFERTILITY; CONGENITAL HYPOTHYROIDISM; CARBOHYDRATE-METABOLISM; ONSET HYPOTHYROIDISM; LUTEINIZING-HORMONE; GONADOTROPIN-LEVELS; OXIDATIVE STRESS; NATIONAL-HEALTH;

D O I：

10.1080/13685538.2024.2310303

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

PurposeTo evaluate the effect of thyroid function on male fertility, focusing on hypo- and hyperthyroidism.MethodsA PubMed/MEDLINE, Web of Science, and Scopus research was performed. Original studies in English published online up to 31 May 2023 were selected and reviewed. The final reference list was defined based on the relevance of each paper to the scope of this review.ResultsThe available data in animals (31 studies) and human (26 studies) showed conflicting results. However, thyroid dysfunction altered erection and ejaculation both in animal models than in men.ConclusionBoth hypothyroidism and hyperthyroidism seem to cause ejaculation and erectile dysfunction. Hence, Guidelines recommend against the systematic screening for thyroid disorders in the men in sub-fertile couples, but only in men with ejaculation and erectile dysfunction and/or altered semen parameters.

引用

页数：12