Role of Fecal Microbiota Transplantation in Managing Clostridium Difficile Infection and Inflammatory Bowel Disease: A Narrative Review

被引：2

作者：

Ghazanfar, Haider ^{[1
]}

Kandhi, Sameer ^{[1
]}

Acherjee, Trishna ^{[1
]}

Qureshi, Zaheer A. ^{[2
]}

Shaban, Mohammed ^{[3
]}

Yordanka, Diaz Saez ^{[1
]}

Cordero, Dessiree ^{[1
]}

Chinta, Siddarth ^{[1
]}

Jyala, Abhilasha ^{[1
]}

Patel, Harish ^{[1
]}

机构：

[1] BronxCare Hlth Syst, Internal Med, Bronx, NY 10457 USA

[2] Quinnipiac Univ, Frank H Netter MD Sch Med, Med, Bridgeport, CT USA

[3] Icahn Sch Med, BronxCare Hosp Ctr, Internal Med, New York, NY USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 12期

关键词：

severe cdi; gut dysbiosis; fecal microbiota transplantation; clostridium difficile; inflammatory bowel disease; SYSTEMATIC REVIEWS; GUT MICROBIOTA; RECURRENT; EPIDEMIOLOGY; REMISSION; EFFICACY; IBD;

D O I：

10.7759/cureus.51004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Fecal microbiota transplantation (FMT) has been emerging as an alternate treatment modality in the management of patients with dysbiosis by restoring abnormal gut microbiota composition through the transplantation of normal fecal microbiota from healthy donors. This technique has lately gained a lot of attention in the treatment of recurrent or refractory Clostridium difficile infection (CDI) owing to its high success rates combined with its favorable safety profile. FMT has also been attracting the interest of clinicians as a new treatment option for inflammatory bowel diseases (IBD). Here, we reviewed most of the recent advancements in the use of FMT for CDI as well as its use in the treatment of IBD.

引用

页数：12

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