Observing hydrogen sulfide in the endoplasmic reticulum of cancer cells and zebrafish by using an activity-based fluorescent probe

被引：30

作者：

Kafuti, Yves S. S. ^{[1
,2
]}

Zeng, Shuang ^{[2
]}

Liu, Xiaosheng ^{[2
]}

Han, Jingjing ^{[3
,4
]}

Qian, Ming ^{[2
]}

Chen, Qixian ^{[2
]}

Wang, Jingyun ^{[1
,2
]}

Peng, Xiaojun ^{[1
]}

Yoon, Juyoung ^{[3
]}

Li, Haidong ^{[1
,2
]}

机构：

[1] Dalian Univ Technol, Frontiers Sci Ctr Smart Mat Oriented Chem Engn, State Key Lab Fine Chem, 2 Linggong Rd, Dalian 116024, Peoples R China

[2] Dalian Univ Technol, Sch Bioengn, 2 Linggong Rd, Dalian 116024, Liaoning, Peoples R China

[3] Ewha Womans Univ, Dept Chem & Nanosci, 52 Ewhayeodae Gil, Seoul 03760, South Korea

[4] Swiss Fed Inst Technol, Dept Biosyst Sci & Engn, Mattenstr 26, CH-4058 Basel, Switzerland

来源：

CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 17期

基金：

中国国家自然科学基金; 新加坡国家研究基金会;

关键词：

QUANTITATIVE DETECTION; IN-VIVO; H2S; VISUALIZATION; MITOCHONDRIA; DESIGN;

D O I：

10.1039/d2cc06645a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A crucial endogenous signaling chemical, hydrogen sulfide, is involved in many physiological actions. In this work, we created the fluorescent probe ER-Nap-NBD using a naphthalimide fluorophore as the signal reporter, a 7-nitro-1,2,3-benzoxadiazole amine as the responsive moiety, and a sulfonamide part for endoplasmic reticulum targeting. ER-Nap-NBD could be detected the H2S levels in solution and in living systems (cells and zebrafish).

引用

收藏

页码：2493 / 2496

页数：4

相关论文

共 40 条

[1] Self-Assembled Nanostructured Tin Oxide Thin Films at the Air-Water Interface for Selective H2S Detection [J].

Bellare, Pavithra ;

Sakhuja, Neha ;

Kundu, Subhajit ;

Bhat, Navakanta ;

Ravishankar, N. .

ACS APPLIED NANO MATERIALS, 2020, 3 (04) :3730-3740

[2] A Review of Hydrogen Sulfide Synthesis, Metabolism, and Measurement: Is Modulation of Hydrogen Sulfide a Novel Therapeutic for Cancer? [J].

Cao, Xu ;

Ding, Lei ;

Xie, Zhi-zhong ;

Yang, Yong ;

Whiteman, Matthew ;

Moore, Philip K. ;

Bian, Jin-Song .

ANTIOXIDANTS & REDOX SIGNALING, 2019, 31 (01) :1-38

[3] Simultaneous Detection of Glutathione and Hydrogen Polysulfides from Different Emission Channels [J].

Chen, Wenqiang ;

Yue, Xiuxiu ;

Zhang, Hui ;

Li, Wenxiu ;

Zhang, Liangliang ;

Xiao, Qi ;

Huang, Chusheng ;

Sheng, Jiarong ;

Song, Xiangzhi .

ANALYTICAL CHEMISTRY, 2017, 89 (23) :12984-12991

[4] An Optical/Photoacoustic Dual-Modality Probe: Ratiometric in/ex Vivo Imaging for Stimulated H2S Upregulation in Mice [J].

Chen, Zhongyan ;

Mu, Xueling ;

Han, Zhong ;

Yang, Shiping ;

Zhang, Changli ;

Guo, Zijian ;

Bai, Yang ;

He, Weijiang .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2019, 141 (45) :17973-17977

[5] Endogenous H2S-Activated Orthogonal Second Near-Infrared Emissive Nanoprobe for In Situ Ratiometric Fluorescence Imaging of Metformin-Induced Liver Injury [J].

Deng, Zhiming ;

Bi, Shenghui ;

Jiang, Mingyang ;

Zeng, Songjun .

ACS NANO, 2021, 15 (02) :3201-3211

[6] Endoplasmic Reticulum-Directed Ratiometric Fluorescent Probe for Quantitive Detection of Basal H2O2 [J].

Gao, Congcong ;

Tian, Yong ;

Zhang, Rubo ;

Jing, Jing ;

Zhang, Xiaoling .

ANALYTICAL CHEMISTRY, 2017, 89 (23) :12945-12950

[7] Near-Infrared Mitochondria-Targetable Fluorescent Probe for High-Contrast Bioimaging of H2S [J].

Gong, Shengyi ;

Zheng, Zhoupeng ;

Guan, Xiaogang ;

Feng, Shumin ;

Feng, Guoqiang .

ANALYTICAL CHEMISTRY, 2021, 93 (14) :5700-5708

[8] Nitrobenzoxadiazole Ether-Based Near-Infrared Fluorescent Probe with Unexpected High Selectivity for H2S Imaging in Living Cells and Mice [J].

Gong, Shengyi ;

Zhou, Enbo ;

Hong, Jiaxin ;

Feng, Guoqiang .

ANALYTICAL CHEMISTRY, 2019, 91 (20) :13136-13142

[9] Palladium Coordination Polymers Nanosheets: New Strategy for Sensitive Photothermal Detection of H2S [J].

He, Suisui ;

Hai, Jun ;

Sun, Shihao ;

Lu, Siyu ;

Wang, Baodui .

ANALYTICAL CHEMISTRY, 2019, 91 (16) :10823-10829

[10] Mitochondria-Targeted Chemosensor to Discriminately and Continuously Visualize HClO and H2S with Multiresponse Fluorescence Signals for In Vitro and In Vivo Bioimaging [J].

He, Xiaojun ;

Zheng, Ziman ;

Zhang, Feifan ;

Xu, Chuchu ;

Xu, Wei ;

Ye, Lisong ;

Sun, Xiaoshuai ;

Zhou, Zhan ;

Shen, Jianliang .

ACS APPLIED BIO MATERIALS, 2020, 3 (11) :7886-7897

← 1 2 3 4 →