Risk Factors and Innovations in Risk Assessment for Melanoma, Basal Cell Carcinoma, and Squamous Cell Carcinoma

被引:14
作者
Wunderlich, K. [1 ]
Suppa, M. [1 ,2 ]
Gandini, S. [3 ]
Lipski, J. [1 ]
White, J. M. [1 ]
Del Marmol, V. [1 ,2 ]
机构
[1] Univ Libre Bruxelles, Hop Erasme, Dept Dermatol, B-1070 Brussels, Belgium
[2] Univ Libre Bruxelles, Inst Jules Bordet, Dept Dermatol, B-1070 Brussels, Belgium
[3] European Inst Oncol, Dept Expt Oncol, Mol & Pharmaco Epidemiol Unit, Mol & Pharmacoepidemiol Unit, I-20139 Milan, Italy
关键词
skin cancer risk factors; melanoma; basal cell carcinoma; squamous cell carcinoma; risk scores; NONMELANOMA SKIN-CANCER; ORGAN TRANSPLANT RECIPIENTS; CUTANEOUS MELANOMA; POOLED-ANALYSIS; ULTRAVIOLET-RADIATION; SUNBED USE; SUSCEPTIBILITY LOCI; ALCOHOL-CONSUMPTION; MELANOCYTIC NEVI; EXPOSURE;
D O I
10.3390/cancers16051016
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Simple Summary Skin cancer is a common, preventable condition of global importance. Different types of skin cancer, like melanoma, basal cell carcinoma, and squamous cell carcinoma, have various risk factors, including UV exposure and genetics. Identifying these risk factors is crucial for targeting early detection and nuanced treatment. Recent research has developed risk scores to identify individuals at high risk, enhancing prevention efforts. This advancement is significant as it improves our ability to detect and treat skin cancer early, ultimately reducing its impact on society.Abstract Skin cancer is the most frequently diagnosed cancer globally and is preventable. Various risk factors contribute to different types of skin cancer, including melanoma, basal cell carcinoma, and squamous cell carcinoma. These risk factors encompass both extrinsic, such as UV exposure and behavioral components, and intrinsic factors, especially involving genetic predisposition. However, the specific risk factors vary among the skin cancer types, highlighting the importance of precise knowledge to facilitate appropriate early diagnosis and treatment for at-risk individuals. Better understanding of the individual risk factors has led to the development of risk scores, allowing the identification of individuals at particularly high risk. These advances contribute to improved prevention strategies, emphasizing the commitment to mitigating the impact of skin cancer.
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页数:24
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