Bispecific Antibodies in the Treatment of Multiple Myeloma

被引：3

作者：

Zhou, Xiang ^{[1
]}

Xiao, Xianghui ^{[1
]}

Kortuem, Klaus Martin ^{[1
]}

Einsele, Hermann ^{[1
,2
]}

机构：

[1] Univ Hosp Wurzburg, Dept Internal Med 2, Wurzburg, Germany

[2] Oberdurrbacher St 6, D-97080 Wurzburg, Germany

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2024年 / 38卷 / 02期

关键词：

Multiple myeloma; Immunotherapy bispecific antibody; CAR T cell; CELL MATURATION ANTIGEN; BONE-MARROW; PRECLINICAL ACTIVITY; MONOCLONAL-ANTIBODY; PLUS LENALIDOMIDE; PLASMA-CELLS; THERAPY; TECLISTAMAB; ADHESION; TARGET;

D O I：

10.1016/j.hoc.2023.12.003

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：361 / 381

页数：21

共 113 条

[1] Understanding the Mechanisms of Resistance to T Cell-based Immunotherapies to Develop More Favorable Strategies in Multiple Myeloma [J].

Ahn, Sungwoo ;

Leblay, Noemie ;

Neri, Paola .

HEMASPHERE, 2021, 5 (06)

[2] Dynamic CD138 surface expression regulates switch between myeloma growth and dissemination [J].

Akhmetzyanova, Ilseyar ;

McCarron, Mark J. ;

Parekh, Samir ;

Chesi, Marta ;

Bergsagel, P. Leif ;

Fooksman, David R. .

LEUKEMIA, 2020, 34 (01) :245-256

[3] Blinatumomab for Acute Lymphoblastic Leukemia: The First Bispecific T-Cell Engager Antibody to Be Approved by the EMA for Minimal Residual Disease [J].

Ali, Sahra ;

Moreau, Alexandre ;

Melchiorri, Daniela ;

Camarero, Jorge ;

Josephson, Filip ;

Olimpier, Odoardo ;

Bergh, Jonas ;

Karres, Dominik ;

Tzogani, Kyriaki ;

Gisselbrecht, Christian ;

Pignatti, Francesco .

ONCOLOGIST, 2020, 25 (04) :E709-E715

[4] Overexpression of G protein-coupled receptor 5D in the bone marrow is associated with poor prognosis in patients with multiple myeloma [J].

Atamaniuk, Johanna ;

Gleiss, Andreas ;

Porpaczy, Edit ;

Kainz, Birgit ;

Grunt, Thomas W. ;

Raderer, Markus ;

Hilgarth, Bernadette ;

Drach, Johannes ;

Ludwig, Heinz ;

Gisslinger, Heinz ;

Jaeger, Ulrich ;

Gaiger, Alexander .

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2012, 42 (09) :953-960

[5] Lenalidomide, Bortezomib, and Dexamethasone with Transplantation for Myeloma [J].

Attal, Michel ;

Lauwers-Cances, Valerie ;

Hulin, Cyrille ;

Leleu, Xavier ;

Caillot, Denis ;

Escoffre, Martine ;

Arnulf, Bertrand ;

Macro, Margaret ;

Belhadj, Karim ;

Garderet, Laurent ;

Roussel, Murielle ;

Payen, Catherine ;

Mathiot, Claire ;

Fermand, Jean P. ;

Meuleman, Nathalie ;

Rollet, Sandrine ;

Maglio, Michelle E. ;

Zeytoonjian, Andrea A. ;

Weller, Edie A. ;

Munshi, Nikhil ;

Anderson, Kenneth C. ;

Richardson, Paul G. ;

Facon, Thierry ;

Avet-Loiseau, Herve ;

Harousseau, Jean-Luc ;

Moreau, Philippe .

NEW ENGLAND JOURNAL OF MEDICINE, 2017, 376 (14) :1311-1320

[6] Clinical Activity of REGN1979, a Bispecific Human, Anti-CD20 x Anti-CD3 Antibody, in Patients with Relapsed/Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (B-NHL) [J].

Bannerji, Rajat ;

Allan, John N. ;

Arnason, Jon E. ;

Brown, Jennifer R. ;

Advani, Ranjana H. ;

Barnes, Jeffrey A. ;

Ansell, Stephen M. ;

O'Brien, Susan M. ;

Chavez, Julio ;

Duell, Johannes ;

David, Kevin A. ;

Martin, Peter ;

Joyce, Robin M. ;

Charnas, Robert ;

Ambati, Srikanth R. ;

Adriaens, Lieve ;

Ufkin, Melanie ;

Zhu, Min ;

Li, Jingjin ;

Gasparini, Peter ;

Ibrahim, Anfal ;

Jankovic, Vladimir ;

Fiaschi, Nathalie ;

Aina, Olulanu ;

Zhang, Wen ;

Deering, Raquel P. ;

Hamon, Sara ;

Thurston, Gavin ;

Murphy, Andrew J. ;

Weinreich, David M. ;

Yancopoulos, George D. ;

Lowy, Israel ;

Sternberg, David ;

Topp, Max S. .

BLOOD, 2019, 134

[7] Emerging Clinical Activity of REGN1979, an Anti-CD20 x Anti-CD3 Bispecific Antibody, in Patients with Relapsed/Refractory Follicular Lymphoma (FL), Diffuse Large B-Cell Lymphoma (DLBCL), and Other B-Cell Non-Hodgkin Lymphoma (B-NHL) Subtypes [J].

Bannerji, Rajat ;

Arnason, Jon E. ;

Advani, Ranjana ;

Brown, Jennifer R. ;

Allan, John N. ;

Ansell, Stephen M. ;

Barnes, Jeffrey ;

O'Brien, Susan M. ;

Chavez, Julio C. ;

Duell, Johannes ;

Lowy, Israel ;

Charnas, Robert ;

Sternberg, David ;

Ambati, Srikanth ;

Adriaens, Lieve ;

Ufkin, Melanie ;

Yan, Xiaoyu ;

Li, Jingjin ;

Navarro, Mark ;

Gasparini, Peter ;

Jankovic, Vladimir ;

Fiaschi, Nathalie ;

Zhang, Wen ;

Hamon, Sara ;

Thurston, Gavin ;

Topp, Max S. .

BLOOD, 2018, 132

[8] Tumor regression in cancer patients by very low doses of a T cell-engaging antibody [J].

Bargou, Ralf ;

Leo, Eugen ;

Zugmaier, Gerhard ;

Klinger, Matthias ;

Goebeler, Mariele ;

Knop, Stefan ;

Noppeney, Richard ;

Viardot, Andreas ;

Hess, Georg ;

Schuler, Martin ;

Einsele, Hermann ;

Brandl, Christian ;

Wolf, Andreas ;

Kirchinger, Petra ;

Klappers, Petra ;

Schmidt, Margit ;

Riethmueller, Gert ;

Reinhardt, Carsten ;

Baeuerle, Patrick A. ;

Kufer, Peter .

SCIENCE, 2008, 321 (5891) :974-977

[9] The making of bispecific antibodies [J].

Brinkmann, Ulrich ;

Kontermann, Roland E. .

MABS, 2017, 9 (02) :182-212

[10] A CS1-NKG2D Bispecific Antibody Collectively Activates Cytolytic Immune Cells against Multiple Myeloma [J].

Chan, Wing Keung ;

Kang, Siwen ;

Youssef, Youssef ;

Glankler, Erin N. ;

Barrett, Emma R. ;

Carter, Alex M. ;

Ahmed, Elshafa H. ;

Prasad, Aman ;

Chen, Luxi ;

Zhang, Jianying ;

Benson, Don M., Jr. ;

Caligiuri, Michael A. ;

Yu, Jianhua .

CANCER IMMUNOLOGY RESEARCH, 2018, 6 (07) :776-787

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