The Story of ECMO

被引:5
作者
Bartlett, Robert H. [1 ]
机构
[1] Univ Michigan, Med Sch, 1025 Forest Rd, Ann Arbor, MI 48105 USA
关键词
EXTRACORPOREAL MEMBRANE-OXYGENATION; CONGENITAL DIAPHRAGMATIC-HERNIA; ACUTE RESPIRATORY-DISTRESS; FAILURE; CIRCULATION; MANAGEMENT; NEWBORN; SUPPORT; BYPASS;
D O I
10.1097/ALN.0000000000004843
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Extracorporeal Circulation in Neonatal Respiratory Failure: A Prospective Randomized Study. By RH Bartlett, DW Roloff, RG Cornell, AF Andrews, PW Dillon, JB Zwischenberger. Pediatrics 1985; 76:479-87.Extracorporeal membrane oxygenation (ECMO) is the use of mechanical devices to replace cardiac and pulmonary function in critical care. In the 1960s, laboratory research showed that extracorporeal circulation could be maintained for days using a membrane oxygenator. In the 1970s, the first clinical trials showed that ECMO could sustain life in severe cardiac and pulmonary failure for days or weeks, leading to organ recovery. From 1980 to 2000, ECMO became standard practice for neonatal and pediatric respiratory and cardiac failure. The critical clinical trial was a prospective randomized trial of ECMO in newborn respiratory failure, published in 1985. This is the classic article reviewed in this publication. This was the first use of a randomized, adaptive design trial to minimize the potential ethical dilemma inherent to clinical trials in which the endpoint is death. Other randomized trials followed, and ECMO is now standard practice for severe respiratory and cardiac failure in all age groups.
引用
收藏
页码:578 / 584
页数:7
相关论文
共 33 条
[1]  
ASHBAUGH DG, 1967, LANCET, V2, P319
[2]   Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the international Extracorporeal Life Support Organization Registry [J].
Barbaro, Ryan P. ;
MacLaren, Graeme ;
Boonstra, Philip S. ;
Combes, Alain ;
Agerstrand, Cara ;
Annich, Gail ;
Diaz, Rodrigo ;
Fan, Eddy ;
Hryniewicz, Katarzyna ;
Lorusso, Roberto ;
Paden, Matthew L. ;
Stead, Christine M. ;
Swol, Justyna ;
Iwashyna, Theodore J. ;
Slutsky, Arthur S. ;
Brodie, Daniel .
LANCET, 2021, 398 (10307) :1230-1238
[3]  
BARTLETT RH, 1985, PEDIATRICS, V76, P479
[4]   DEVELOPMENT OF A MEMBRANE OXYGENATOR - OVERCOMING BLOOD DIFFUSION LIMITATION [J].
BARTLETT, RH ;
KITTREDGE, D ;
NOYES, BS ;
WILLARD, RH ;
DRINKER, PA .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1969, 58 (06) :795-+
[5]   PROLONGED PARTIAL VENOARTERIAL BYPASS - PHYSIOLOGIC, BIOCHEMICAL, AND HEMATOLOGIC RESPONSES [J].
BARTLETT, RH ;
FONG, SW ;
BURNS, NE ;
GAZZANIGA, AB .
ANNALS OF SURGERY, 1974, 180 (06) :850-856
[6]  
BARTLETT RH, 1982, SURGERY, V92, P425
[7]  
BARTLETT RH, 1976, T AM SOC ART INT ORG, V22, P80
[8]  
Bartlett RH., 1969, SURG FORUM, V20, pl52
[9]   Esperanza: The First Neonatal ECMO Patient [J].
Bartlett, Robert H. .
ASAIO JOURNAL, 2017, 63 (06) :832-832
[10]   Clinical Research in Acute Fatal Illness: Lessons From Extracorporeal Membrane Oxygenation [J].
Bartlett, Robert H. .
JOURNAL OF INTENSIVE CARE MEDICINE, 2016, 31 (07) :456-465