OUTCOMES OF ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION IN A COHORT OF CARDIOGENIC SHOCK PATIENTS UNDERGOING PRIMARY PERCUTANEOUS CORONARY INTERVENTION

被引：0

作者：

Kumar, Rajesh ^{[1
]}

Khan, Kamran Ahmed ^{[1
]}

Rahooja, Kubbra ^{[1
]}

Chachar, Kalsoom ^{[1
]}

Khan, Muhammad Qasim ^{[1
]}

Ali, Ahsan ^{[1
]}

Bin Naseer, Ali ^{[1
]}

Basit, Abdul ^{[1
]}

Rasool, Muhammad ^{[1
]}

Safdar, Uroosa ^{[1
]}

Urooj, Abiha ^{[1
]}

Hussain, Aisha ^{[1
]}

Ishaq, Muhammad ^{[1
]}

Wadhwa, Anesh ^{[2
]}

Farooq, Fawad ^{[1
]}

Khan, Sohail ^{[1
]}

Sial, Jawaid Akbar ^{[1
]}

机构：

[1] Natl Inst Cardiovasc Dis NICVD, Karachi, Pakistan

[2] Dow Univ Hlth Sci DUHS, Karachi, Pakistan

来源：

PAKISTAN HEART JOURNAL | 2023年 / 56卷 / 02期

关键词：

ST-segment elevation myocardial infarction; cardiogenic shock; primary percutaneous coronary intervention; MACE; PREDICTORS; MANAGEMENT; MORTALITY;

D O I：

10.47144/phj.v56i2.2578

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objectives: The objective of this study was to investigate the immediate and short-term mortality rates among patients with ST-segment elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS) who underwent primary percutaneous coronary intervention (PCI). Methodology: This observational study was conducted at a tertiary care cardiac center in Pakistan. We included consecutive patients diagnosed with STEMI complicated by CS who underwent primary PCI. We analyzed the clinical characteristics, management strategies, and in-hospital as well as short-term follow-up outcomes of the patients. Results: A total of 200 patients were included in the study, of which 74.5% (149) were male, and the mean age was 57.96 +/- 12.52 years. The majority of patients were classified as Killip class III (64.0%, 128), while the remaining were classified as Killip class IV. On arrival, arrhythmias were observed in 37.5% (75) of the patients, 27.5% (55) were in cardiac arrest and 84.5% (169) required intubation. Intra-aortic balloon pump (IABP) placement was performed in 31.5% (63) of the patients, and temporary pacemakers (TPM) were placed in 18.5% (37). The in-hospital mortality rate was found to be 10.5% (21). During a mean follow- up period of 177 days (141.5-212.5), a cumulative major adverse cardiovascular event (MACE) was observed in 48% (96) of the patients, with an all-cause mortality rate of 28% (56). Additionally, re-infarction occurred in 7.5% (15) of the patients, and re-hospitalization due to heart failure was noted in 23.5% (47) of the patients. Conclusion: Our study revealed an in-hospital mortality rate of 10.5% following primary PCI in patients with CS. At approximately six months after the acute event, nearly half of the patients experienced MACE, with a notable mortality rate of 28%. These findings highlight the critical nature of CS and emphasize the need for further research and interventions to improve outcomes in this high-risk patient population.

引用

页码：157 / 162

页数：6

共 18 条

[1] Palliative care referral in ST-segment elevation myocardial infarction complicated with cardiogenic shock in the United States [J].