Stress, inflammation, microbiome and depression

被引:18
作者
Medina-Rodriguez, Eva M. [1 ,3 ,4 ]
Cruz, Alyssa A. [1 ]
De Abreu, Julia Cavati [1 ]
Beurel, Eleonore [1 ,2 ]
机构
[1] Dept Psychiat & Behav Sci, Los Angeles, CA USA
[2] Univ Miami, Miller Sch Med, Dept Biochem & Mol Biol, Miami, FL 33136 USA
[3] Vet Affairs Med Ctr, Bruce W Carter Dept, Miami, FL 33125 USA
[4] Univ Miami, Miller Sch Med, 1011 NW 15th St,Gautier Bldg Room 414, Miami, FL 33136 USA
关键词
Stress; Inflammation; Microbiome; Depression; LACTOBACILLUS-HELVETICUS R0052; BIFIDOBACTERIUM-LONGUM R0175; IRRITABLE-BOWEL-SYNDROME; EARLY-LIFE STRESS; GUT MICROBIOTA; FECAL MICROBIOTA; PROBIOTIC TREATMENT; IMMUNE ACTIVATION; DOUBLE-BLIND; BACTERIA;
D O I
10.1016/j.pbb.2023.173561
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Psychiatric disorders are mental illnesses involving changes in mood, cognition and behavior. Their prevalence has rapidly increased in the last decades. One of the most prevalent psychiatric disorders is major depressive disorder (MDD), a debilitating disease lacking efficient treatments. Increasing evidence shows that microbial and immunological changes contribute to the pathophysiology of depression and both are modulated by stress. This bidirectional relationship constitutes the brain-gut axis involving various neuroendocrine, immunological, neuroenterocrine and autonomic pathways. The present review covers the most recent findings on the relationships between stress, the gut microbiome and the inflammatory response and their contribution to depression.
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页数:10
相关论文
共 158 条
[121]   Acute and repeated exposure to social stress reduces gut microbiota diversity in Syrian hamsters [J].
Partrick, Katherine A. ;
Chassaing, Benoit ;
Beach, Linda Q. ;
McCann, Katharine E. ;
Gewirtz, Andrew T. ;
Huhman, Kim L. .
BEHAVIOURAL BRAIN RESEARCH, 2018, 345 :39-48
[122]   The gut microbiome regulates the increases in depressive-type behaviors and in inflammatory processes in the ventral hippocampus of stress vulnerable rats [J].
Pearson-Leary, Jiah ;
Zhao, Chunyu ;
Bittinger, Kyle ;
Eacret, Darrell ;
Luz, Sandra ;
Vigderman, Abigail S. ;
Dayanim, Gabriel ;
Bhatnagar, Seema .
MOLECULAR PSYCHIATRY, 2020, 25 (05) :1068-1079
[123]   Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort [J].
Qin, Youwen ;
Havulinna, Aki S. ;
Liu, Yang ;
Jousilahti, Pekka ;
Ritchie, Scott C. ;
Tokolyi, Alex ;
Sanders, Jon G. ;
Valsta, Liisa ;
Brozynska, Marta ;
Zhu, Qiyun ;
Tripathi, Anupriya ;
Vazquez-Baeza, Yoshiki ;
Loomba, Rohit ;
Cheng, Susan ;
Jain, Mohit ;
Niiranen, Teemu ;
Lahti, Leo ;
Knight, Rob ;
Salomaa, Veikko ;
Inouye, Michael ;
Meric, Guillaume .
NATURE GENETICS, 2022, 54 (02) :134-+
[124]   Comparison of (R)-ketamine and lanicemine on depression-like phenotype and abnormal composition of gut microbiota in a social defeat stress model [J].
Qu, Youge ;
Yang, Chun ;
Ren, Qian ;
Ma, Min ;
Dong, Chao ;
Hashimoto, Kenji .
SCIENTIFIC REPORTS, 2017, 7
[125]   The microbiome: A key regulator of stress and neuroinflammation [J].
Rea, Kieran ;
Dinan, Timothy G. ;
Cryan, John F. .
NEUROBIOLOGY OF STRESS, 2016, 4 :23-33
[126]   A Potential Role for Stress-Induced Microbial Alterations in IgA-Associated Irritable Bowel Syndrome with Diarrhea [J].
Rengarajan, Sunaina ;
Knoop, Kathryn A. ;
Rengarajan, Arvind ;
Chai, Jiani N. ;
Grajales-Reyes, Jose G. ;
Samineni, Vijay K. ;
Russler-Germain, Emilie, V ;
Ranganathan, Prabha ;
Fasano, Alessio ;
Sayuk, Gregory S. ;
Gereau, Robert W. ;
Kau, Andrew L. ;
Knights, Dan ;
Kashyap, Purna C. ;
Ciorba, Matthew A. ;
Newberry, Rodney D. ;
Hsieh, Chyi-Song .
CELL REPORTS MEDICINE, 2020, 1 (07)
[127]   A double-blind, randomized, placebo-controlled trial of Lactobacillus helveticus and Bifidobacterium longum for the symptoms of depression [J].
Romijn, Amy R. ;
Rucklidge, Julia J. ;
Kuijer, Roeline G. ;
Frampton, Chris .
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, 2017, 51 (08) :810-821
[128]   Probiotic Lactobacillus Plantarum 299v decreases kynurenine concentration and improves cognitive functions in patients with major depression: A double-blind, randomized, placebo controlled study [J].
Rudzki, Leszek ;
Ostrowska, Lucyna ;
Pawlak, Dariusz ;
Malus, Aleksandra ;
Pawlak, Krystyna ;
Waszkiewicz, Napoleon ;
Szulc, Agata .
PSYCHONEUROENDOCRINOLOGY, 2019, 100 :213-222
[129]   The human stress response [J].
Russell, Georgina ;
Lightman, Stafford .
NATURE REVIEWS ENDOCRINOLOGY, 2019, 15 (09) :525-534
[130]   Gut microbiota and major depressive disorder: A systematic review and meta-analysis [J].
Sanada, Kenji ;
Nakajima, Shinichiro ;
Kurokawa, Shunya ;
Barcelo-Soler, Alberto ;
Ikuse, Daisuke ;
Hirata, Akihito ;
Yoshizawa, Akira ;
Tomizawa, Yoshihiro ;
Salas-Valero, Montserrat ;
Noda, Yoshihiro ;
Mimura, Masaru ;
Iwanami, Akira ;
Kishimoto, Taishiro .
JOURNAL OF AFFECTIVE DISORDERS, 2020, 266 :1-13