Identification of Growth-Related SNPs and Genes in the Genome of the Pearl Oyster (Pinctada fucata) Using GWAS

被引：1

作者：

Zhao, Mingming ^{[1
]}

Thaimuangphol, Wipavee ^{[2
]}

Hong, Yujie ^{[1
]}

Yan, Ziqi ^{[1
]}

Chen, Zongfa ^{[1
]}

Jin, Minxuan ^{[1
]}

Zheng, Anna ^{[1
]}

Wang, Bei ^{[1
,3
]}

Wang, Zhongliang ^{[1
,3
]}

机构：

[1] Guangdong Ocean Univ, Coll Fisheries, Zhanjiang 524088, Peoples R China

[2] Mahasarakham Univ, Fac Technol,Lab Fish Immunol & Nutrigen, Div Fisheries, Appl Anim & Aquat Sci Res Unit, Maha Sarakham 44150, Thailand

[3] Guangdong Prov Key Lab Aquat Anim Dis Control & Hl, Zhanjiang 524088, Peoples R China

来源：

FISHES | 2023年 / 8卷 / 06期

关键词：

Pinctada fucata; GWAS; growth; SNPs; genome-wide resequencing; aquaculture; QUANTITATIVE TRAIT LOCI; VI COLLAGEN; CELL-ADHESION; LINKAGE MAP; ASSOCIATION; TRANSCRIPTOME; FRAMEWORK;

D O I：

10.3390/fishes8060296

中图分类号：

S9 [水产、渔业];

学科分类号：

0908 ;

摘要：

Pinctada fucata, the pearl oyster, is a bivalve primarily cultivated for the production of saltwater pearls. In this study, the genome-wide association study (GWAS) for the growth-related traits and a principal components analysis (PCA) in P. fucata were performed. Genomic parameters of 6 growth-related traits in 60 individuals were estimated by using 4,937,162 single-nucleotide polymorphisms (SNPs). A total of 45 SNPs associated with growth traits were thus identified. Furthermore, 165 candidate genes were identified, including collagen alpha-3 (VI), serine/threonine-protein kinase mos-like harboring significant markers, and histidine-rich protein PFHRP-III-like, which may influence growth-related traits associated with various biological processes. The results of this study can facilitate marker-assisted selection and breeding programs designed to enhance growth and also offer a theoretical foundation for the further development and utilization of genomic resources in P. fucata.

引用

页数：12

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