A Comprehensive Treatment Protocol for Endometriosis Patients Decreases Pain and Improves Function

被引:5
作者
Shrikhande, Allyson [1 ,2 ]
Patil, Soha [1 ,2 ]
Subhan, Merzia [1 ,2 ]
Moody, Erika [1 ,2 ]
Natarajan, Janaki [1 ,2 ]
Tailor, Yogita [1 ,2 ]
Mamsaang, Marjorie [1 ,2 ]
James, Neha [1 ,2 ]
Leishear, Kimberlee [1 ,2 ]
Vyas, Rakhi [1 ,2 ]
Sandhu, Sandra [1 ,2 ]
Ahmed, Tayyaba [1 ,2 ]
Filart, Rosemarie [1 ,2 ]
Daniel, Gabrielle [1 ,2 ]
Orbuch, Iris Kerin [3 ,4 ]
Larish, Yaniv [1 ,2 ]
Liu, Lora [1 ,2 ]
机构
[1] Pelv Rehabil Med Clin Res Fdn, W Palm Beach, FL 33401 USA
[2] Feinstein Inst Med Res, Manhasset, NY 11030 USA
[3] Providence St Johns Hosp, Santa Monica, CA USA
[4] Adv Gynecol Laparoscopy Ctr, Los Angeles, CA USA
关键词
chronic pelvic pain; peripheral sensitization; central sensitization; myofascial dysfunction; CHRONIC PELVIC PAIN; QUALITY-OF-LIFE; NEUROGENIC INFLAMMATION; SENSITIZATION; BLADDER; DEPRESSION; ANXIETY; IMPACT; WOMEN; MODEL;
D O I
10.2147/IJWH.S365637
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Purpose: The purpose of this paper is to evaluate the efficacy of a multimodal, outpatient neuromuscular protocol in treating remaining sensitization and myofascial pain in endometriosis patients post-surgical excision. Patients and Methods: A retrospective longitudinal study was conducted for women aged 22 to 78 with a history of surgically excised endometriosis. 60 women with an average duration of pain of 8.63 +/- 7.65 years underwent a treatment protocol consisting of ultrasound guided trigger point injections, peripheral nerve blocks, and pelvic floor physical therapy for 6 weeks. Concomitant cognitive behavioral therapy once weekly for a total of 12 weeks was also undertaken. Pain intensity and pelvic functionality were assessed at new patient consults and 3-month follow ups using Visual Analogue Scale (VAS) and Functional Pelvic Pain Scale (FPPS). Results: At new patient consults, average VAS and FPPS were 7.45 +/- 2.11 (CI 6.92-7.98) and 14.35 +/- 6.62 (CI 12.68 -16.02), respectively. At 3-month follow ups, average VAS and FPPS decreased to 4.12 +/- 2.44 (CI 3.50-4.73; p < 0.001) and 10.3 +/- 6.55 (CI 8.64-11.96; p < 0.001), respectively. Among FPPS categories, sleeping, intercourse, and working showed the highest statistical significance. Conclusion: Data suggests the multimodal protocol was effective in treating the remaining underlying sensitization and myofascial pain seen in Endometriosis patients post-surgical excision, particularly in decreasing pain and improving function during work and intercourse.
引用
收藏
页码:91 / 101
页数:11
相关论文
共 44 条
[41]   Surgical and anatomical landmarks for the perineal branch of the posterior femoral cutaneous nerve: implications in perineal pain syndromes Laboratory investigation [J].
Tubbs, R. Shane ;
Miller, Joseph ;
Loukas, Marios ;
Shoja, Mohammadali M. ;
Shokouhi, Ghaffar ;
Cohen-Gadol, Aaron A. .
JOURNAL OF NEUROSURGERY, 2009, 111 (02) :332-335
[42]   Central sensitization: Implications for the diagnosis and treatment of pain [J].
Woolf, Clifford J. .
PAIN, 2011, 152 (03) :S2-S15
[43]   Advances in the Treatment of Neuropathic Pain [J].
Xu, Li ;
Zhang, Yuguan ;
Huang, Yuguang .
TRANSLATIONAL RESEARCH IN PAIN AND ITCH, 2016, 904 :117-129
[44]   Effect of lidocaine on histamine release and Ca2+ mobilization from mast cells and basophils [J].
Yanagi, H ;
Sankawa, H ;
Saito, H ;
Iikura, Y .
ACTA ANAESTHESIOLOGICA SCANDINAVICA, 1996, 40 (09) :1138-1144