Impact of liver cirrhosis, severity of cirrhosis and portal hypertension on the difficulty of laparoscopic and robotic minor liver resections for primary liver malignancies in the anterolateral segments

被引：3

作者：

Zheng, Junhao ^{[1
]}

Liang, Xiao ^{[1
]}

Wu, Andrew G. R. ^{[2
]}

Kabir, Tousif ^{[3
]}

Scatton, Olivier ^{[4
]}

Lim, Chetana ^{[4
]}

Hasegawa, Kiyoshi ^{[5
]}

Sijberden, Jasper P. ^{[6
]}

Aghayan, Davit L. ^{[7
,8
]}

Siow, Tiing Foong ^{[9
]}

Dokmak, Safi ^{[10
]}

Herman, Paulo ^{[11
]}

Marino, Marco V. ^{[12
,13
]}

Mazzaferro, Vincenzo ^{[14
,15
]}

Chiow, Adrian K. H. ^{[16
]}

Sucandy, Iswanto ^{[17
]}

Ivanecz, Arpad ^{[18
]}

Choi, Sung Hoon ^{[19
]}

Lee, Jae Hoon ^{[20
]}

Prieto, Mikel ^{[21
]}

Vivarelli, Marco ^{[22
]}

Giuliante, Felice ^{[23
]}

Ruzzenente, Andrea ^{[24
]}

Yong, Chee-Chien ^{[25
]}

Yin, Mengqiu ^{[26
]}

Chen, Zewei ^{[26
]}

Fondevila, Constantino ^{[27
,28
]}

Efanov, Mikhail ^{[29
]}

Morise, Zenichi ^{[30
]}

Di Benedetto, Fabrizio ^{[31
]}

Brustia, Raffaele ^{[32
]}

Dalla Valle, Raffaele ^{[33
]}

Boggi, Ugo ^{[34
]}

Geller, David ^{[35
]}

Belli, Andrea ^{[36
]}

Memeo, Riccardo ^{[37
]}

Gruttadauria, Salvatore ^{[38
,39
]}

Mejia, Alejandro ^{[40
]}

Park, James O. ^{[41
]}

Rotellar, Fernando ^{[42
]}

Choi, Gi-Hong ^{[43
,44
]}

Robles-Campos, Ricardo ^{[45
]}

Wang, Xiaoying ^{[46
]}

Sutcliffe, Robert P. ^{[47
]}

Pratschke, Johann ^{[48
,49
,50
,51
]}

Lai, Eric C. H. ^{[52
]}

Chong, Charing C. N. ^{[53
]}

D'Hondt, Mathieu ^{[54
]}

Monden, Kazuteru ^{[55
]}

Lopez-Ben, Santiago ^{[56
]}

机构：

[1] Zhejiang Univ, Sch Med, Sir Run Run Shaw Hosp, Dept Gen Surg, Hangzhou, Peoples R China

[2] Natl Univ Singapore, Yong Loo Lin Sch Med, Singapore, Singapore

[3] Sengkang Gen Hosp, Dept Gen Surg, Singapore, Singapore

[4] Sorbonne Univ, Dept Digest HBP & Liver Transplantat, Hop Pitie Salpetriere, Paris, France

[5] Univ Tokyo, Grad Sch Med, Dept Surg, Hepatobiliary Pancreat Surg Div, Tokyo, Japan

[6] Fdn Poliambulanza, Dept Surg, Brescia, Italy

[7] Univ Oslo, Intervent Ctr, Oslo, Norway

[8] Univ Oslo, Oslo Univ Hosp, Inst Clin Med, Dept HPB Surg, Oslo, Norway

[9] Far Eastern Mem Hosp, Dept Surg, Div Gen Surg, New Taipei City, Taiwan

[10] Univ Paris Cite, Beaujon Hosp, Dept HPB Surg & Liver Transplantat, Clichy, France

[11] Univ Sao Paulo, Sch Med, Dept Gastroenterol, Liver Surg Unit, Sao Paulo, Brazil

[12] Azienda Osped Riuniti Villa Sofia Cervello, Dept Gen Surg, Palermo, Italy

[13] F Tappeiner Hosp, Dept Gen Surg, Merano, Italy

[14] Fdn IRCCS Ist Nazl Tumori Milano, HPB Surg & Liver Transplantat, Milan, Italy

[15] Univ Milan, Milan, Italy

[16] Changi Gen Hosp, Dept Surg, Hepatopancreatobiliary Unit, Singapore, Singapore

[17] AdventHealth Tampa, Digest Hlth Inst, Tampa, FL USA

[18] Univ Med Ctr Maribor, Dept Abdominal & Gen Surg, Maribor, Slovenia

[19] CHA Univ, Sch Med, CHA Bundang Med Ctr, Dept Gen Surg, Seongnam, South Korea

[20] Univ Ulsan, Coll Med, Asan Med Ctr, Div Hepatobiliary & Pancreat Surg,Dept Surg, Seoul 138736, South Korea

[21] Univ Basque Country, Univ Cruces Hosp, Biocruces Bizkaia Hlth Res Inst, Hepatobiliary Surg & Liver Transplantat Unit, Bilbao, Spain

[22] Polytech Univ Marche, United Hosp Ancona, HPB Surg & Transplantat Unit, Dept Expt & Clin Med, I-60020 Ancona, Italy

[23] Univ Cattolica Sacro Cuore, Fdn Policlin Univ A Gemelli, IRCCS, Hepatobiliary Surg Unit, Rome, Italy

[24] Univ Verona, GB Rossi Hosp, Dept Surg Dent Gynecol & Pediat, Gen & Hepatobiliary Surg, Verona, Italy

[25] Chang Gung Mem Hosp, Dept Surg, Kaohsiung, Taiwan

[26] Zhejiang Univ, Sch Med, Affiliated Jinhua Hosp, Dept Hepatobiliary Surg, Jinhua, Peoples R China

[27] Univ Barcelona, Hosp Clin, Gen & Digest Surg Serv, IDIBAPS,CIBERehd, Barcelona, Spain

[28] Hosp Univ La Paz, Gen & Digest Surg, IdiPAZ, CIBERehd, Madrid, Spain

[29] Moscow Clin Sci Ctr, Dept Hepatopancreato Biliary Surg, Moscow, Russia

[30] Fujita Hlth Univ, Okazaki Med Ctr, Sch Med, Dept Surg, Okazaki, Aichi, Japan

[31] Univ Modena & Reggio Emilia, HPB Surg & Liver Transplant Unit, Modena, Italy

[32] Henri Mondor Hosp, AP HP, Dept Digest & Hepatobiliary & Pancreat Surg, Creteil, France

[33] Univ Parma, Dept Med & Surg, Hepatobiliary Surg Unit, Parma, Italy

[34] Univ Pisa, Div Gen & Transplant Surg, Pisa, Italy

[35] Univ Pittsburgh, Med Ctr, Dept Surg, Div Hepatobiliary & Pancreat Surg, Pittsburgh, PA USA

[36] Natl Canc Ctr IRCCS G Pascale, Div Hepatopancreatobiliary Surg Oncol, Dept Abdominal Oncol, Naples, Italy

[37] F Miulli Gen Reg Hosp, Unit Hepatopancreat Biliary Surg, Bari, Italy

[38] Univ Pittsburgh Med Ctr Italy, Dept Treatment & Study Abdominal Dis & Abdominal, Ist Ricovero & Cura Carattere Sci, Ist Mediterraneo & Trapianti & Terapie Ad Alta Sp, Palermo, Italy

[39] Univ Catania, Dept Gen Surg & Med Surg Specialties, Catania, Italy

[40] Methodist Dallas Med Ctr, Liver Inst, Dallas, TX USA

[41] Univ Washington, Med Ctr, Dept Surg, Seattle, WA 98195 USA

[42] Univ Navarra, Clin Univ Navarra, Dept Gen Surg, HPB & Liver Transplant Unit, Pamplona, Spain

[43] Yonsei Univ, Severance Hosp, Dept Surg, Div Hepatopancreatobiliary Surg,Coll Med, Seoul, South Korea

[44] Inst Hlth Res Navarra IdisNA, Pamplona, Spain

[45] Clin & Univ Hosp Virgen de La Arrixaca, IMIB ARRIXACA, Dept Gen Visceral & Transplantat Surg, Murcia, Spain

[46] Fudan Univ, Zhongshan Hosp, Liver Canc Inst, Dept Liver Surg & Transplantat, Shanghai, Peoples R China

[47] Univ Hosp Birmingham NHS Trust, Dept Hepatopancreatobiliary & Liver Transplant Su, Birmingham, England

[48] Campus Charite Mitte, Dept Surg, Berlin, Germany

[49] Charite, Campus Virchow Klinikum, Berlin, Germany

[50] Free Univ Berlin, Berlin, Germany

来源：

EJSO | 2024年 / 50卷 / 01期

关键词：

Laparoscopic liver; Laparoscopic hepatectomy; Minimally-invasive liver; Minimally-invasive hepatectomy; Cirrhosis; Difficulty score; RECOMMENDATIONS; PROPOSAL; SURGERY;

D O I：

10.1016/j.ejso.2023.107252

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Introduction: We performed this study in order to investigate the impact of liver cirrhosis (LC) on the difficulty of minimally invasive liver resection (MILR), focusing on minor resections in anterolateral (AL) segments for primary liver malignancies.Methods: This was an international multicenter retrospective study of 3675 patients who underwent MILR across 60 centers from 2004 to 2021.Results: 1312 (35.7%) patients had no cirrhosis, 2118 (57.9%) had Child A cirrhosis and 245 (6.7%) had Child B cirrhosis. After propensity score matching (PSM), patients in Child A cirrhosis group had higher rates of open conversion (p = 0.024), blood loss >500 mls (p = 0.001), blood transfusion (p < 0.001), postoperative morbidity (p = 0.004), and in-hospital mortality (p = 0.041). After coarsened exact matching (CEM), Child A cirrhotic patients had higher open conversion rate (p = 0.05), greater median blood loss (p = 0.014) and increased postoperative morbidity (p = 0.001). Compared to Child A cirrhosis, Child B cirrhosis group had longer post-operative stay (p = 0.001) and greater major morbidity (p = 0.012) after PSM, and higher blood transfusion rates (p = 0.002), longer postoperative stay (p < 0.001), and greater major morbidity (p = 0.006) after CEM. After PSM, patients with portal hypertension experienced higher rates of blood loss >500 mls (p = 0.003) and intraoperative blood transfusion (p = 0.025).Conclusion: The presence and severity of LC affect and compound the difficulty of MILR for minor resections in the AL segments. These factors should be considered for inclusion into future difficulty scoring systems for MILR.

引用

页数：11

共 26 条

[21] Systematic review and meta-analysis of difficulty scoring systems for laparoscopic and robotic liver resections [J].

Linn, Yun-Le ;

Wu, Andrew G. ;

Han, Ho-Seong ;

Liu, Rong ;

Chen, Kuo-Hsin ;

Fuks, David ;

Soubrane, Olivier ;

Cherqui, Daniel ;

Geller, David ;

Cheung, Tan-To ;

Edwin, Bjorn ;

Aldrighetti, Luca ;

Abu Hilal, Mohammad ;

Troisi, Roberto, I ;

Wakabayashi, Go ;

Goh, Brian K. P. .

JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, 2023, 30 (01) :36-59

[22] Nomenclature of hepatic anatomy and resections: a review of the Brisbane 2000 system [J].

Strasberg, SM .

JOURNAL OF HEPATO-BILIARY-PANCREATIC SURGERY, 2005, 12 (05) :351-355

[23] Laparoscopic and open liver resection for hepatocellular carcinoma with Child-Pugh B cirrhosis: multicentre propensity score-matched study [J].

Troisi, R., I ;

Berardi, G. ;

Morise, Z. ;

Cipriani, F. ;

Ariizumi, S. ;

Sposito, C. ;

Panetta, V ;

Simonelli, I ;

Kim, S. ;

Goh, B. K. P. ;

Kubo, S. ;

Tanaka, S. ;

Takeda, Y. ;

Ettorre, G. M. ;

Russolillo, N. ;

Wilson, G. C. ;

Cimino, M. ;

Montalti, R. ;

Giglio, M. C. ;

Igarashi, K. ;

Chan, C. Y. ;

Torzilli, G. ;

Cheung, T. T. ;

Mazzaferro, V ;

Kaneko, H. ;

Ferrero, A. ;

Geller, D. A. ;

Han, H. S. ;

Kanazawa, A. ;

Wakabayashi, G. ;

Aldrighetti, L. ;

Yamamoto, M. .

BRITISH JOURNAL OF SURGERY, 2021, 108 (02) :196-204

[24] What has changed after the Morioka consensus conference 2014 on laparoscopic liver resection? [J].

Wakabayashi, Go .

HEPATOBILIARY SURGERY AND NUTRITION, 2016, 5 (04) :281-289

[25] Recommendations for Laparoscopic Liver Resection A Report From the Second International Consensus Conference Held in Morioka [J].

Wakabayashi, Go ;

Cherqui, Daniel ;

Geller, David A. ;

Buell, Joseph E. ;

Kaneko, Hironori ;

Han, Ho Seong ;

Asbun, Horacio ;

O'Rourke, Nicholas ;

Tanabe, Minoru ;

Koffron, Alan J. ;

Tsung, Allan ;

Soubrane, Olivier ;

Machado, Marcel Autran ;

Gayet, Brice ;

Troisi, Roberto I. ;

Pessaux, Patrick ;

Van Dam, Ronald M. ;

Scatton, Olivier ;

Abu Hilal, Mohammad ;

Belli, Giulio ;

Kwon, Choon Hyuck David ;

Edwin, Bjorn ;

Choi, Gi Hong ;

Aldrighetti, Luca Antonio ;

Cai, Xiujun ;

Clemy, Sean ;

Chen, Kuo-Hsin ;

Schoen, Michael R. ;

Sugioka, Atsushi ;

Tang, Chung-Ngai ;

Herman, Paulo ;

Pekolj, Juan ;

Chen, Xiao-Ping ;

Dagher, Ibrahim ;

Jarnagin, William ;

Yamamoto, Masakazu ;

Strong, Russell ;

Jagannath, Palepu ;

Lo, Chung-Mau ;

Clavien, Pierre-Alain ;

Kokudo, Norihiro ;

Barkun, Jeffrey ;

Strasberg, Steven M. .

ANNALS OF SURGERY, 2015, 261 (04) :619-629

[26] Influence of Child-Pugh B7 and B8/9 cirrhosis on laparoscopic liver resection for hepatocellular carcinoma: a retrospective cohort study [J].

Watanabe, Yukihiro ;

Aikawa, Masayasu ;

Kato, Tomotaka ;

Takase, Kenichiro ;

Watanabe, Yuichiro ;

Okada, Katsuya ;

Okamoto, Kojun ;

Koyama, Isamu .

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2023, 37 (02) :1316-1333

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