Effect of malnutrition on outcomes of hospitalisations for acute pulmonary embolism: a national inpatient database study

被引:2
作者
Li, Si [1 ]
Lio, Ka U. [1 ]
Ho, Truong-An [2 ]
Wang, Yichen [3 ]
Rali, Parth [2 ]
机构
[1] Temple Univ, Dept Med, Lewis Katz Sch Med, Philadelphia, PA 19122 USA
[2] Temple Univ, Lewis Katz Sch Med, Dept Thorac Med & Surg, Philadelphia, PA USA
[3] Univ Penn, Perelman Sch Med, Dept Med, Philadelphia, PA USA
关键词
Malnutrition; Pulmonary disease; OBJECTIVE NUTRITIONAL INDEXES; IMPACT;
D O I
10.1136/bmjnph-2023-000705
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Background To evaluate the occurrence of malnutrition in pulmonary embolism (PE)-related hospitalisations and assess the impact of malnutrition on the outcomes of patients with PE.Methods A retrospective observational study using data extracted from the Nationwide Inpatient Sample from 2016 to 2018. Hospitalisations with a principal diagnosis of PE were obtained using International Classification of Diseases, Tenth Revision codes and divided into groups based on a secondary diagnosis of malnutrition.Results Of 563 135 PE hospitalisations, 30 495 (5.4%) had malnutrition. PE patients with malnutrition were older (mean age +/- SD, 69.1 +/- 14.5 vs 62.3 +/- 16.6, p<0.001) and with higher Charlson Comorbidity Index score (3 to 5, 24.8% vs 12.9%, p<0.001). Concurrent malnutrition was associated with higher adjusted OR (aOR) of in-hospital mortality (aOR 2.43, 95% CI 2.18 to 2.70, p<0.001), acute kidney injury (aOR 1.56, 95% CI 1.45 to 1.67, p<0.001), sepsis (aOR 4.37, 95% CI 3.79 to 5.03, p<0.001), shock (aOR 2.52, 95% CI 2.25 to 2.81, p<0.001), acidosis (aOR 2.55, 95% CI 2.34 to 2.77, p<0.001) and mechanical ventilation (aOR 2.95, 95% CI 2.61 to 3.33, p<0.001). Patients with PE and malnutrition had an increased mean length of stay (adjusted difference 3.39 days, 95% CI 3.14 to 3.65, p<0.001), hospital charges (adjusted difference US$34 802.11, 95% CI US$31 005.01 to US$38 599.22, p<0.001) and costs (adjusted difference US$8 332.01, 95% CI US$7489.09 to US$9174.94, p<0.001).Conclusion Concurrent PE and malnutrition were associated with worse outcomes. The study highlights the importance of identifying malnutrition in patients with PE to improve outcomes and reduce healthcare utilisation.
引用
收藏
页码:188 / 195
页数:8
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