Immunotherapy responses of patients with metastatic melanoma are linked to IL-17 signaling

被引：1
|
作者：
Varaljai, Renata [1 ]
Roesch, Alexander [1 ]
机构：
[1] Univ Hosp Essen, Dept Dermatol, Essen, Germany
来源：
NATURE CANCER | 2023年 / 4卷 / 09期
关键词：
D O I：
10.1038/s43018-023-00611-1
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Treatment with immune checkpoint inhibitors (ICIs) has improved the survival of patients with metastatic melanoma. However, although ICIs are promising for achieving lasting clinical responses, only a subset of patients receive substantial benefit. Our results suggest that the IL-17 pathway supports the response of melanoma to dual ICI therapy and might represent a biomarker for patient stratification.
引用
收藏
页码：1224 / 1225
页数：2
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