Immunotherapy responses of patients with metastatic melanoma are linked to IL-17 signaling

被引：1

作者：

Varaljai, Renata ^{[1
]}

Roesch, Alexander ^{[1
]}

机构：

[1] Univ Hosp Essen, Dept Dermatol, Essen, Germany

来源：

NATURE CANCER | 2023年 / 4卷 / 09期

关键词：

D O I：

10.1038/s43018-023-00611-1

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Treatment with immune checkpoint inhibitors (ICIs) has improved the survival of patients with metastatic melanoma. However, although ICIs are promising for achieving lasting clinical responses, only a subset of patients receive substantial benefit. Our results suggest that the IL-17 pathway supports the response of melanoma to dual ICI therapy and might represent a biomarker for patient stratification.

引用

页码：1224 / 1225

页数：2

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