Base-Promoted S-Arylation of Sulfenamides for the Synthesis of Sulfilimines

被引：25

作者：

Zhou, Qinglong ^{[1
]}

Li, Jiaomeng ^{[1
]}

Wang, Tianyi ^{[1
]}

Yang, Xing ^{[1
]}

机构：

[1] Hunan Normal Univ, Coll Chem & Chem Engn, Key Lab Chem Biol & Tradit Chinese Med, Key Lab Assembly & Applicat Organ Funct Mol Hunan, Changsha 410081, Peoples R China

来源：

ORGANIC LETTERS | 2023年 / 25卷 / 23期

基金：

中国国家自然科学基金;

关键词：

CATALYZED IMINATION; NITRENE TRANSFER; SULFIDES; SULFOXIMINES; SULFIMIDES; SULFOXIDES; ATOM;

D O I：

10.1021/acs.orglett.3c01436

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sulfiliminesare key intermediates to common motifs in medicinesand agrochemicals. Typically, this class of compounds are preparedby imidation of thioethers, transition-metal-catalyzed or base-promotedsulfur alkylation and transition-metal-catalyzed sulfur arylation.Here, we report a practical and efficient base-mediated sulfur arylationreaction for the preparation of sulfilimines. A wide range of N-acyl and N-aryl sulfenamides react withvarious diaryliodonium salts smoothly to afford the sulfilimines inhigh yields with excellent chemoselectivities.

引用

页码：4335 / 4339

页数：5

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