Anorectal melanoma Update on clinical presentation, diagnosis and treatment

被引：1

作者：

Matull, Johanna ^{[1
]}

Kreuter, Alexander ^{[1
,2
]}

Wehry, Ulrich-Peter ^{[1
]}

Michalowitz, Alena-Lioba ^{[1
]}

机构：

[1] Univ Witten Herdecke, Klin Dermatol Venerol & Allergol, Helios St Elisabeth Klin Oberhausen, Josefstr 3, D-46045 Oberhausen, Germany

[2] Univ Witten Herdecke, Klin Dermatol Venerol & Allergol, Helios St Johannes Klin Duisburg, Duisburg, Germany

来源：

DERMATOLOGIE | 2024年 / 75卷 / 01期

基金：

英国科研创新办公室;

关键词：

Mucosal melanoma; Immunotherapy; Surgical procedures; Adjuvant radiotherapy; Local excision; RESECTED STAGE-III; MUCOSAL MELANOMAS; OPEN-LABEL; MALIGNANT-MELANOMA; RECTAL MELANOMA; IPILIMUMAB; ADJUVANT; NIVOLUMAB; PEMBROLIZUMAB; SURVIVAL;

D O I：

10.1007/s00105-023-05252-0

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Anorectal melanomas are a rare malignant type of cancer and pose a diagnostic challenge due to their hidden anatomical location. They are associated with nonspecific clinical symptoms and are therefore often misinterpreted as benign disease. The result is delayed diagnosis in the locally advanced or metastasized stage and an unfavorable prognosis. Given the overall low incidence of the tumor, no consensus guidelines for diagnosis or therapy are established either internationally or nationally at present. The present work intends to provide a comprehensive overview of the clinical aspects, diagnostics, and therapeutic approaches of anorectal melanoma based on the currently available literature.

引用

页码：15 / 21

页数：7

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