Application of experimental design as a statistical approach to recover bioactive peptides from different food sources

被引：0
作者：
de Albuquerque Mendes, Mikael Kelvin [1 ]
Oliveira, Christian Bremmer dos Santos [1 ]
Medeiros, Carla Mariana da Silva [1 ]
Dantas, Clecio [2 ]
Carrilho, Emanuel [3 ]
Nogueira, Ana Rita de Araujo [4 ]
Lopes Junior, Cicero Alves [1 ]
Vieira, Edivan Carvalho [1 ]
机构：
[1] Univ Fed Piaui UFPI, Dept Quim, POB 64049550, Teresina, Piaui, Brazil
[2] Univ Estadual Maranhao UEMA, Dept Quim, POB 65604380, Caxias, MMaranhao, Brazil
[3] Univ Sao Paulo, Inst Quim Sao Carlos, BR-13566590 Sao Carlos, SP, Brazil
[4] Embrapa Pecuaria Sudeste, BR-13560970 Sao Carlos, SP, Brazil
来源：
FOOD SCIENCE AND BIOTECHNOLOGY | 2024年 / 33卷 / 07期
基金：
巴西圣保罗研究基金会;
关键词：
Design of experiments; Response surface methodology; Enzymatic hydrolysis; Bioactive peptides (BAPs); Proteins; Biological activities; RESPONSE-SURFACE METHODOLOGY; BOX-BEHNKEN DESIGN; ENZYMATIC-HYDROLYSIS; FUNCTIONAL-PROPERTIES; ANTIOXIDANT PROPERTIES; MICROEXTRACTION METHOD; PROTEIN HYDROLYSATE; PROTEOLYTIC-ENZYMES; PLACKETT-BURMAN; IN-VITRO;
D O I：
10.1007/s10068-024-01540-0
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Bioactive peptides (BAPs) derived from samples of animals and plants have been widely recommended and consumed for their beneficial properties to human health and to control several diseases. This work presents the applications of experimental designs (DoE) used to perform factor screening and/or optimization focused on finding the ideal hydrolysis condition to obtain BAPs with specific biological activities. The collection and discussion of articles revealed that Box Behnken Desing and Central Composite Design were the most used. The main parameters evaluated were pH, time, temperature and enzyme/substrate ratio. Among vegetable protein sources, soy was the most used in the generation of BAPs, and among animal proteins, milk and shrimp stood out as the most explored sources. The degree of hydrolysis and antioxidant activity were the most investigated responses in obtaining BAPs. This review brings new information that helps researchers apply these DoE to obtain high-quality BAPs with the desired biological activities.
引用
收藏
页码：1559 / 1583
页数：25
相关论文
共 102 条
  • [11] Application of multivariate optimization for the selective extraction of phenolic compounds in cashew nuts (Anacardium occidentale L.)
    de Albuquerque Mendes, Mikael Kelvin
    dos Santos Oliveira, Christian Bremmer
    Alves Veras, Marcia Denise
    Araujo, Bruno Quirino
    Dantas, Clecio
    Chaves, Mariana Helena
    Lopes Junior, Cicero Alves
    Vieira, Edivan Carvalho
    [J]. TALANTA, 2019, 205
  • [12] de Barros Neto B., 2001, COMO FAZER EXPERIMEN
  • [13] Soy protein hydrolysis with microbial protease to improve antioxidant and functional properties
    de Oliveira, Cibele Freitas
    Folmer Correa, Ana Paula
    Coletto, Douglas
    Daroit, Daniel Joner
    Cladera-Olivera, Florencia
    Brandelli, Adriano
    [J]. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 2015, 52 (05): : 2668 - 2678
  • [14] Production of antioxidant hydrolyzates from a whey protein concentrate with thermolysin: Optimization by response surface methodology
    del Mar Contreras, Maria
    Hernandez-Ledesma, Blanca
    Amigo, Lourdes
    Martin-Alvarez, Pedro J.
    Recio, Isidra
    [J]. LWT-FOOD SCIENCE AND TECHNOLOGY, 2011, 44 (01) : 9 - 15
  • [15] Evaluation of physicochemical and functional properties of spray-dried protein hydrolysate from non-penaeid shrimp (Acetes indicus)
    Dhanabalan, Vignaesh
    Xavier, Martin
    Murthy, Lakshmi N.
    Asha, Kurukkan K.
    Balange, Amjad K.
    Nayak, Binaya B.
    [J]. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2020, 100 (01) : 50 - 58
  • [16] Optimization of pea protein hydrolysate preparation and purification of antioxidant peptides based on an in silico analytical approach
    Ding, Jie
    Liang, Rong
    Yang, Yiying
    Sun, Na
    Lin, Songyi
    [J]. LWT-FOOD SCIENCE AND TECHNOLOGY, 2020, 123
  • [17] Enzymatic Hydrolysis of Chicken Viscera to Obtain Added-Value Protein Hydrolysates with Antioxidant and Antihypertensive Properties
    dos Santos Aguilar, Jessika Goncalves
    Santos de Souza, Ana Karoliny
    Soares de Castro, Ruann Janser
    [J]. INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, 2020, 26 (02) : 717 - 725
  • [18] Improving antioxidant activity of black bean protein by hydrolysis with protease combinations
    dos Santos Aguilar, Jessika Goncalves
    Cason, Victor Granato
    Soares de Castro, Ruann Janser
    [J]. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 2019, 54 (01) : 34 - 41
  • [19] Enzymatic hydrolysis and microbial fermentation: The most favorable biotechnological methods for the release of bioactive peptides
    Elisa Cruz-Casas, Dora
    Aguilar, Cristobal N.
    Ascacio-Valdes, Juan A.
    Rodriguez-Herrera, Raul
    Chavez-Gonzalez, Monica L.
    Flores-Gallegos, Adriana C.
    [J]. FOOD CHEMISTRY: MOLECULAR SCIENCES, 2021, 3
  • [20] Controlled enzymatic hydrolysis for improved exploitation of the antioxidant potential of wheat gluten
    Elmalimadi, Mohamed B.
    Jovanovic, Jelena R.
    Stefanovic, Andrea B.
    Tanaskovic, Sonja Jakovetic
    Djurovic, Sanja B.
    Bugarski, Branko M.
    Knezevic-Jugovic, Zorica D.
    [J]. INDUSTRIAL CROPS AND PRODUCTS, 2017, 109 : 548 - 557
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